Evidence map›Paper›PMID 378479›Full record

ArticleClinical and experimental immunology1979

The role of circulating immune complexes in the glomerular disease of experimental hepatosplenic schistosomiasis.

M Digeon, D Droz, L H Noel, J Riza, C Rieumailhol, J F Bach, F Santoro, A Capron

Open access · greenAbstract read
In one paragraph

Article in Clinical and experimental immunology, 1979. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Immunopathogenesis of experimental IgA nephropathy.Springer seminars in immunopathology · 1994
    Review
  4. Immunopathology of Schistosoma mansoni infection.Clinical microbiology reviews · 1989
    Review
  5. Article
  6. Article
  7. Article
  8. Mesangial IgA nephritis.Springer seminars in immunopathology · 1982
    Review
  9. Article
  10. IgA glomerular deposits in experimental cirrhosis.The American journal of pathology · 1981
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M Digeon
D Droz
L H Noel
J Riza
C Rieumailhol
J F Bach
F Santoro
A Capron

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The serological and renal changes were studied simultaneously in 115 mice infected with Schistosoma mansoni. IgG and IgM, but not IgA anti-S. mansoni antibodies were detected in the sera, together with circulating immune complexes containing schistosomal antigen. Glomerular mesangial deposits of IgA, IgM and C3 were observed. Despite the strong correlation observed between the occurrence of the circulating immune complexes containing schistosomal antigen and the glomerular deposits, results concerning the behaviour of IgA suggest that portal hypertension and liver damage have a role in the pathogenesis of glomerular lesions.

Indexed as

Antigen-Antibody ComplexAnimalsFemaleFluorescent Antibody TechniqueImmunoglobulinsKidney DiseasesKidney GlomerulusLiver DiseasesMiceSchistosoma mansoniSchistosomiasisSplenic DiseasesAntigen-Antibody ComplexImmunoglobulins

Identifiers

PMID378479
PMCPMC1537623
OpenAlexW1584048269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.