Evidence map›Paper›PMID 37847594›Full record

ArticleVeterinary medicine and science2023

Antifungal susceptibility profile of yeasts isolated from the oral cavity of cats.

Donya Nikaein, Dariush Shirani, Aghil Sharifzadeh, Ava Alavi, Ali Reza Khosravi

Open access · goldAbstract read
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Article in Veterinary medicine and science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Donya NikaeinMycology Research Center, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.ORCID 0000-0003-2333-3361
Dariush ShiraniDepartment of Small Animal Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Aghil SharifzadehMycology Research Center, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Ava AlaviMycology Research Center, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Ali Reza KhosraviMycology Research Center, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.ORCID 0000-0002-6777-5930
University of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicroorganisms living in the oral cavity play an important role in health and disease of the host. Cats are susceptible to oral infections, and it is documented that fungi in the oral cavity could impact these infections. Antifungal resistance has been increasing in recent years.

objectivesThis study was designed to identify yeast isolates from the oral cavity of healthy cats and to evaluate their antifungal susceptibility pattern.

methodsOral specimens were collected from 60 cats and cultured at 37°C for 10 days. Yeasts were isolated and identified. Their antifungal susceptibility pattern was determined according to CLSI M44-A.

resultsThree yeast genera were isolated, including Candida spp (55.5%), Rhodotorula spp (33.3%) and Hanseniaspora spp (11.1%). Antifungal susceptibility profiling showed that, apart from a dose-dependent effect of itraconazole, Hanseniaspora spp was susceptible to all seven drugs studied. The Candida species were susceptible to all drugs except ketoconazole (sensitivity 80%) and caspofungin (sensitivity 40%). In R. glutinis and R. minuta, 100% sensitivity was observed for amphotericin B, posaconazole, ketoconazole and voriconazole.

conclusionsThe results suggest that, in comparison with humans and other animals, cats have a different oral mycoflora in terms of species, number and diversity. However, these isolates have similar susceptibility patterns to those seen in isolates from other animals and humans. More studies should be done to further characterize the oral mycobiota of cats and its role in oral infections.

Indexed as

Antifungal AgentsKetoconazoleAnimalsCandidaCatsFluconazoleHumansMicrobial Sensitivity TestsMouthRhodotorulaYeastsAntifungal AgentsFluconazoleKetoconazoleantifungal susceptibilityCandida sppdisk diffusionHanseniaspora spporal cavityRhodotorula spp

Identifiers

PMID37847594
PMCPMC10650235
OpenAlexW4387701525

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.