ArticleJMIR mental health2023
A Motivational Interviewing Chatbot With Generative Reflections for Increasing Readiness to Quit Smoking: Iterative Development Study.
Article in JMIR mental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effectiveness of Digital Interventions to Increase Preventive Care Uptake in Older Adults: Systematic Review.JMIR aging · 2026Pooled it
- Social Media Support Groups for Youth Nicotine Vaping Cessation: An RCT.American journal of preventive medicine · 2026Trial
- Impact of Computer-Mediated Versus Face-to-Face Motivational-Type Interviews on Participants' Language and Subsequent Cannabis Use: Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Structured Large Language Model Workflows for Motivational Interviewing in Health Behavior Change: Proof-of-Concept Study.JMIR formative research · 2026Article
- Performance of a large language model in the informed consent process for participation in a clinical trial.NPJ digital medicine · 2026Article
- Use of the Dynamic Systems Development Method to Inform Technology-Assisted Motivational Interviewing (TAMI) for Tobacco Cessation: Qualitative Study.JMIR formative research · 2026Article
- Evaluation of an Artificial Intelligence Conversational Chatbot to Enhance HIV Preexposure Prophylaxis Uptake: Development and Usability Internal Testing.Journal of medical Internet research · 2026Article
- The Development and Use of AI Chatbots for Health Behavior Change: Scoping Review.Journal of medical Internet research · 2026Article
- AI-Enabled Personalized Smoking Cessation Intervention With the Aipaca Chatbot: Mixed Methods Feasibility Study.JMIR formative research · 2025Observational
- Protocol for a randomized clinical trial to evaluate the effectiveness of a technology-assisted motivational interviewing (TAMI) chatbot on smoking cessation.Contemporary clinical trials · 2025Article
- New Doc on the Block: Scoping Review of AI Systems Delivering Motivational Interviewing for Health Behavior Change.Journal of medical Internet research · 2025Article
- Artificial Intelligence in Health Promotion and Disease Reduction: Rapid Review.Journal of medical Internet research · 2025Review
- The Impact of ChatGPT Exposure on User Interactions With a Motivational Interviewing Chatbot: Quasi-Experimental Study.JMIR formative research · 2025Article
- Collecting initial accounts using ChatCharlie chatbot improves eyewitness memory in later investigative interviews.Scientific reports · 2025Article
- Achieving clinically meaningful outcomes in digital health: a six-step, cyclical precision engagement framework (ENGAGE).Frontiers in digital health · 2025Article
- Generation of Backward-Looking Complex Reflections for a Motivational Interviewing-Based Smoking Cessation Chatbot Using GPT-4: Algorithm Development and Validation.JMIR mental health · 2024Article
- Neural Conversational Agent for Weight Loss Counseling: Protocol for an Implementation and Feasibility Study.JMIR research protocols · 2024Article
- Year 2023 in Biomedical Natural Language Processing: a Tribute to Large Language Models and Generative AI.Yearbook of medical informatics · 2024Article
- A systematic review of chatbot-assisted interventions for substance use.Frontiers in psychiatry · 2024Article
- Designing a just-in-time adaptive intervention with trigger detection and a generative chatbot: Smoking cessation use case.Digital healthArticle
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe motivational interviewing (MI) approach has been shown to help move ambivalent smokers toward the decision to quit smoking. There have been several attempts to broaden access to MI through text-based chatbots. These typically use scripted responses to client statements, but such nonspecific responses have been shown to reduce effectiveness. Recent advances in natural language processing provide a new way to create responses that are specific to a client's statements, using a generative language model.
objectiveThis study aimed to design, evolve, and measure the effectiveness of a chatbot system that can guide ambivalent people who smoke toward the decision to quit smoking with MI-style generative reflections.
methodsOver time, 4 different MI chatbot versions were evolved, and each version was tested with a separate group of ambivalent smokers. A total of 349 smokers were recruited through a web-based recruitment platform. The first chatbot version only asked questions without reflections on the answers. The second version asked the questions and provided reflections with an initial version of the reflection generator. The third version used an improved reflection generator, and the fourth version added extended interaction on some of the questions. Participants' readiness to quit was measured before the conversation and 1 week later using an 11-point scale that measured 3 attributes related to smoking cessation: readiness, confidence, and importance. The number of quit attempts made in the week before the conversation and the week after was surveyed; in addition, participants rated the perceived empathy of the chatbot. The main body of the conversation consists of 5 scripted questions, responses from participants, and (for 3 of the 4 versions) generated reflections. A pretrained transformer-based neural network was fine-tuned on examples of high-quality reflections to generate MI reflections.
resultsThe increase in average confidence using the nongenerative version was 1.0 (SD 2.0; P=.001), whereas for the 3 generative versions, the increases ranged from 1.2 to 1.3 (SD 2.0-2.3; P<.001). The extended conversation with improved generative reflections was the only version associated with a significant increase in average importance (0.7, SD 2.0; P<.001) and readiness (0.4, SD 1.7; P=.01). The enhanced reflection and extended conversations exhibited significantly better perceived empathy than the nongenerative conversation (P=.02 and P=.004, respectively). The number of quit attempts did not significantly change between the week before the conversation and the week after across all 4 conversations.
conclusionsThe results suggest that generative reflections increase the impact of a conversation on readiness to quit smoking 1 week later, although a significant portion of the impact seen so far can be achieved by only asking questions without the reflections. These results support further evolution of the chatbot conversation and can serve as a basis for comparison against more advanced versions.
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