Evidence map›Paper›PMID 37847454›Full record

ArticleAnnals of intensive care2023

Effects of CPAP and FiO

Lorenzo Giosa, Patrick Duncan Collins, Martina Sciolla, Francesca Cerrone, Salvatore Di Blasi, Matteo Maria Macrì, Luca Davicco, Andrea Laguzzi, Fabiana Gorgonzola, Roberto Penso and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of intensive care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Using the helmet.Intensive care medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 3 countries.

Lorenzo GiosaDepartment of Critical Care Medicine, Guy's and St. Thomas' National Health Service Foundation Trust, St. Thomas' Hospital, Westminster Bridge Road, London, SE17EH, UK. lorenzo.giosa@gmail.com.ORCID http://orcid.org/0000-0002-0145-5125
Patrick Duncan CollinsDepartment of Critical Care Medicine, Guy's and St. Thomas' National Health Service Foundation Trust, St. Thomas' Hospital, Westminster Bridge Road, London, SE17EH, UK.
Martina SciollaDepartment of Pulmonary Medicine, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Francesca CerroneUniversity of Turin, Turin, Italy.
Salvatore Di BlasiDepartment of Anesthesia and Critical Care, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Matteo Maria MacrìDepartment of Anesthesia and Critical Care, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Luca DaviccoDepartment of Anesthesia and Critical Care, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Andrea LaguzziDepartment of Anesthesia and Critical Care, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Fabiana GorgonzolaDepartment of Pulmonary Medicine, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Roberto PensoDepartment of Anesthesia and Critical Care, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Irene SteinbergDepartment of Surgical Sciences, University of Turin, Turin, Italy.
Massimo MuracciniDepartment of Surgical Sciences, University of Turin, Turin, Italy.
Alberto PerboniDepartment of Pulmonary Medicine, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Vincenzo RussottoDepartment of Anesthesia and Critical Care, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Luigi CamporotaDepartment of Critical Care Medicine, Guy's and St. Thomas' National Health Service Foundation Trust, St. Thomas' Hospital, Westminster Bridge Road, London, SE17EH, UK.
Giacomo BellaniCentre for Medical Sciences - CISMed, University of Trento, Trento, Italy.
Pietro CaironiDepartment of Anesthesia and Critical Care, AOU S. Luigi Gonzaga, Orbassano, Turin, Italy.
Ospedale San Luigi Gonzaga · ITNational Health Service · GBUniversity of Turin · ITUniversity of Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundin COVID-19 acute respiratory failure, the effects of CPAP and FiO

methodsIn this single-center (S.Luigi Gonzaga University-Hospital, Turin, Italy), randomized, crossover study, we included patients receiving Helmet-CPAP for early (< 48 h) COVID-19 pneumonia without additional cardiac or respiratory disease. Healthy subjects were included as controls. Participants were equipped with an esophageal catheter, a non-invasive cardiac output monitor, and an arterial catheter. The protocol consisted of a random sequence of non-rebreather mask (NRB), Helmet-CPAP (with variable positive pressure and FiO

resultsWe enrolled 28 COVID-19 patients and 7 healthy controls. In all patients, respiratory effort increased from NRB to Helmet-CPAP (5.0 ± 3.7 vs 8.3 ± 3.9 cmH

conclusionsIn early COVID-19 pneumonia, Helmet-CPAP increases respiratory effort without altering dynamic stress, while the effects upon static and total stress are variable, requiring individual assessment. Oxygen masks with higher FiO

Indexed as

COVID-19Gas-exchangeHelmet-CPAPHemodynamicsLung stressNon-rebreather maskRespiratory effortRespiratory failureVenturi mask

Identifiers

PMID37847454
PMCPMC10581975
OpenAlexW4387692651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.