Evidence map›Paper›PMID 37847208›Full record

Observational studyBlood transfusion = Trasfusione del sangue2024

Challenges in perioperative blood transfusions in kidney transplantation and the need for Patient Blood Management.

Diana Rodríguez-Espinosa, José J Broseta, Anney Rosario, Judit Cacho, Beatriz Tena, Elena Cuadrado-Payan, Ramsés Marrero, Beatriu Bayés, Nuria Esforzado, Mireia Musquera and 3 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Blood transfusion = Trasfusione del sangue, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Diana Rodríguez-EspinosaDepartment of Nephrology and Renal Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain.
José J BrosetaDepartment of Nephrology and Renal Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain.
Anney RosarioDepartment of Nephrology and Renal Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain.
Judit CachoDepartment of Nephrology and Renal Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain.
Beatriz TenaDepartment of Anaesthesia and Perioperative Care, Hospital Clínic of Barcelona, Barcelona, Spain.
Elena Cuadrado-PayanDepartment of Nephrology and Renal Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain.
Ramsés MarreroDepartment of Anaesthesia and Perioperative Care, Hospital Clínic of Barcelona, Barcelona, Spain.
Beatriu BayésDepartment of Nephrology and Renal Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain.
Nuria EsforzadoDepartment of Nephrology and Renal Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain.
Mireia MusqueraDepartment of Urology, Hospital Clínic of Barcelona, Barcelona, Spain.
Fritz DiekmannDepartment of Nephrology and Renal Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain.
Aleix CasesDepartment of Nephrology and Renal Transplantation, Hospital Clínic of Barcelona, Barcelona, Spain.
Misericordia BasoraDepartment of Anaesthesia and Perioperative Care, Hospital Clínic of Barcelona, Barcelona, Spain.
Hospital Clínic de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnemia is highly prevalent in end-stage chronic kidney disease patients, increasing their risk of receiving blood transfusions during and on the days after a kidney transplant (KTx) surgery. However, there is currently a lack of data that thoroughly describes this phenomenon in this population, the associated risk factors, and how they could benefit from the application of Patient Blood Management (PBM) guidelines. MATERIALS AND

methodsObservational study. All adult patients who received a KTx between January 1

resultsWe found that a high amount (39%) of KTx recipients required at least one blood transfusion during the perioperative period. And that 1) most of these patients had anemia at the time of transplantation (85.4%), 2) iron status upon admission was associated with the transfusion of more blood units (3.9 vs 2.7, p=0.019), 3) surgical reintervention (OR 7.28, 2.35-22.54) and deceased donor donation (OR 1.99, 1.24-3.21) were associated with an increased risk of transfusion, and finally, 4) there was an association between a higher number of blood units transfused and impaired kidney graft function six months after hospital discharge (1.6 vs 1.9, p=0.02).

conclusionsIn conclusion, PBM guidelines should be applied to patients on the KTx deceased donor waiting list and especially those scheduled to receive a transplant from a living donor. This could potentially increase the utilization efficiency of blood products and avoid transfusion-related severe adverse effects.

Indexed as

AnemiaBlood TransfusionKidney TransplantationAdultAgedFemaleHumansKidney Failure, ChronicMaleMiddle AgedPerioperative CareRisk Factors

Identifiers

PMID37847208
PMCPMC11073621
OpenAlexW4387691880

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.