Evidence map›Paper›PMID 37846645›Full record

ArticleInternational health2024

Persons 'never treated' in mass drug administration for lymphatic filariasis: identifying programmatic and research needs from a series of research review meetings 2020-2021.

Molly A Brady, Emily Toubali, Margaret Baker, Elizabeth Long, Caitlin Worrell, Kapa Ramaiah, Patricia Graves, T Deirdre Hollingsworth, Louise Kelly-Hope, Diana Stukel and 4 more

Open access · goldAbstract read
In one paragraph

Article in International health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  10. New Tools and Nuanced Interventions to Accelerate Achievement of the 2030 Roadmap for Neglected Tropical Diseases.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 5 countries.

Molly A BradyDepartment of Global Health, RTI International, Washington, DC 20008, USA.
Emily ToubaliNeglected Tropical Diseases Division, Office of Infectious Disease, Bureau for Global Health, United States Agency for International Development, Washington, DC 20547, USA.
Margaret BakerDepartment of Global Health, RTI International, Washington, DC 20008, USA.
Elizabeth LongNeglected Tropical Diseases Support Center, Task Force for Global Health, Decatur, GA 30030, USA.
Caitlin WorrellDivision of Parasitic Diseases and Malaria, U.S. Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Kapa RamaiahConsultant, Lymphatic Filariasis Epidemiologist, Pondicherry, India.
Patricia GravesCollege of Public Health, Medical and Veterinary Sciences and WHO Collaborating Centre for Vector-Borne and Neglected Tropical Diseases, James Cook University, Nguma-bada Campus, Cairns, QLD 4870, Australia.
T Deirdre HollingsworthBig Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, OX3 7LF, UK.ORCID 0000-0001-5962-4238
Louise Kelly-HopeLiverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.
Diana StukelAct to End Neglected Tropical Diseases West, Department of Global Health and Population, FHI 360, Washington, DC 20009, USA.
Bhupendra TripathiBill and Melinda Gates Foundation, India Country Office, New Delhi 110067, India.
Arianna Rubin MeansDepartment of Global Health, University of Washington, Seattle, WA, USA.
Sultani Hadley MatendecheroKenya National Public Health Institute, PO Box 30016-00100, GPO Nairobi, Kenya.
Alison KrentelSchool of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Drive, Ottawa, ON K1G 5Z3, Canada.ORCID 0000-0001-7213-1577
RTI International · USCenters for Disease Control and Prevention · USFamily Health International 360 · USJames Cook University · AUThe Task Force for Global Health · USUnited States Agency for International Development · USUniversity of Liverpool · GBUniversity of Ottawa · CAUniversity of Oxford · GBUniversity of Washington · US

Funding

Bill and Melinda Gates FoundationBritish GovernmentIntramural CDC HHS CC999999United States Agency for International Development
6 · The paper itself

Abstract

As neglected tropical disease programs rely on participation in rounds of mass drug administration (MDA), there is concern that individuals who have never been treated could contribute to ongoing transmission, posing a barrier to elimination. Previous research has suggested that the size and characteristics of the never-treated population may be important but have not been sufficiently explored. To address this critical knowledge gap, four meetings were held from December 2020 to May 2021 to compile expert knowledge on never treatment in lymphatic filariasis (LF) MDA programs. The meetings explored four questions: the number and proportion of people never treated, their sociodemographic characteristics, their infection status and the reasons why they were not treated. Meeting discussions noted key issues requiring further exploration, including how to standardize measurement of the never treated, adapt and use existing tools to capture never-treated data and ensure representation of never-treated people in data collection. Recognizing that patterns of never treatment are situation specific, participants noted measurement should be quick, inexpensive and focused on local solutions. Furthermore, programs should use existing data to generate mathematical models to understand what levels of never treatment may compromise LF elimination goals or trigger programmatic action.

Indexed as

Elephantiasis, FilarialFilaricidesMass Drug AdministrationHumansFilaricidesadherencecomplianceeliminationequityfilariasismass drug administration

Identifiers

PMID37846645
PMCPMC11021373
OpenAlexW4387691801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.