Evidence map›Paper›PMID 37846593›Full record

ArticleDevelopment (Cambridge, England)2023

Abscisic acid biosynthesis is necessary for full auxin effects on hypocotyl elongation.

Ryan J Emenecker, Joseph Cammarata, Irene Yuan, Caroline Howard, Shekufeh Ebrahimi Naghani, Helene S Robert, Eiji Nambara, Lucia C Strader

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Natural variation links seedling hypocotyl growth with water loss in Arabidopsis.The Plant journal : for cell and molecular biology · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ryan J EmeneckerDepartment of Biology, Washington University, St. Louis, MO 63130, USA.
Joseph CammarataDepartment of Biology, Duke University, Durham, NC 27708, USA.
Irene YuanDepartment of Biology, Washington University, St. Louis, MO 63130, USA.
Caroline HowardDepartment of Biology, Duke University, Durham, NC 27708, USA.
Shekufeh Ebrahimi NaghaniMendel Centre for Genomics and Proteomics of Plant Systems , CEITEC MU - Central European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0002-1486-0699
Helene S RobertMendel Centre for Genomics and Proteomics of Plant Systems , CEITEC MU - Central European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0002-6610-836X
Eiji NambaraDepartment of Cell & Systems Biology, University of Toronto, Toronto, ON M5S 3B2, Canada.
Lucia C StraderCenter for Biomolecular Condensates, Washington University, St. Louis, MO 63130, USA.ORCID 0000-0002-7600-7204
Duke University · USCentral European Institute of Technology · CZWashington University in St. Louis · USUniversity of Toronto · CA

Funding

NIGMS administrative equipment supplement for R35 GM136338-02R35GM136338 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Lucia Strader · 2020 to 2026
$3.2M
NIGMS NIH HHS R35 GM136338NIH HHS R35 GM136338
6 · The paper itself

Abstract

In concert with other phytohormones, auxin regulates plant growth and development. However, how auxin and other phytohormones coordinately regulate distinct processes is not fully understood. In this work, we uncover an auxin-abscisic acid (ABA) interaction module in Arabidopsis that is specific to coordinating activities of these hormones in the hypocotyl. From our forward genetics screen, we determine that ABA biosynthesis is required for the full effects of auxin on hypocotyl elongation. Our data also suggest that ABA biosynthesis is not required for the inhibitory effects of auxin treatment on root elongation. Our transcriptome analysis identified distinct auxin-responsive genes in root and shoot tissues, which is consistent with differential regulation of growth in these tissues. Further, our data suggest that many gene targets repressed upon auxin treatment require an intact ABA pathway for full repression. Our results support a model in which auxin stimulates ABA biosynthesis to fully regulate hypocotyl elongation.

Indexed as

ArabidopsisArabidopsis ProteinsAbscisic AcidGene Expression Regulation, PlantHypocotylIndoleacetic AcidsPlant Growth RegulatorsAbscisic AcidArabidopsis ProteinsIndoleacetic AcidsPlant Growth RegulatorsAbscisic acidAuxinPhytohormonePhytohormone interactionsPlant development

Identifiers

PMID37846593
PMCPMC10730017
OpenAlexW4387692446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.