Evidence map›Paper›PMID 37846293›Full record

ArticleOral oncology reports2023

Post biphosphonate mandible osteonecrosis: A case study and literature review.

Bambara H Aboubacar, Zerbo Nina Assanatou Jumelle, Valerie Odero-Marah, Ki Thierry Romuald, Oué Draogo Y C Laetitia, Konsem Tarcissus

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oral oncology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Bambara H AboubacarUFR/SDS, Joseph KI-ZERBO University, 03 BP 7021 Ouagadougou 03, Burkina Faso.
Zerbo Nina Assanatou JumelleClinical Hematology Oncology Department, CHU Bogodogo, 01 BP371 Ouagadougou 01, Burkina Faso.
Valerie Odero-MarahCenter for Urban Health Disparities Research and Innovation, Department of Biology, Morgan State University, 1700 East Cold Spring Lane, Baltimore, MD, USA.
Ki Thierry RomualdRadiology Department, CHU SANOU SOURO, 01 BP 676 Bobo Dioulasso 01, Burkina Faso.
Oué Draogo Y C LaetitiaMaxillofacial Surgery Department, CHU Yalgado Ouedraogo, 03 BP 7022 Ouagadougou 03, Burkina Faso.
Konsem TarcissusUFR/SDS, Joseph KI-ZERBO University, 03 BP 7021 Ouagadougou 03, Burkina Faso.
Centre Hospitalier Universitaire Yalgado Ouédraogo · BFMorgan State University · USUniversité Joseph Ki-Zerbo · BFWest African Health Organisation · BF

Funding

Wastewater surveillance for addressing environmental health disparitiesU54MD013376 · NIMHD · MORGAN STATE UNIVERSITY · PI Payam Sheikhattari · 2019 to 2026
$33.5M
To Investigate Molecular Mechanisms of Aging-Related Growth of the Prostate - Implications in Prostate Tumorigenesis and Cancer TreatmentU54MD007590 · NIMHD · CLARK ATLANTA UNIVERSITY · PI Mustapha Alhassan · 2019 to 2026
$17.1M
NIMHD NIH HHS U54 MD007590NIMHD NIH HHS U54 MD013376
6 · The paper itself

Abstract

Purpose: Bisphosphonates have proven effective in reducing pain and skeletal events in bone metastases treatment. However, there is a long-term complication called osteonecrosis of the jaw, which has been reported for more than a decade. Despite various professional recommendations, there is no international consensus on the best therapeutic strategy. Prevention is crucial, and a multidisciplinary approach must be tailored to each stage of the condition. Design: We present a case of osteonecrosis of the jaw in a patient with metastatic breast cancer who was receiving 4 mg injectable zoledronic acid. Result: The patient stopped treatment with zoledronic acid and received systemic treatment (analgesics, antibiotics), with the resolution of symptoms. Conclusion: ONJ is a serious condition associated with taking BP that can impact oral health and quality of life. Our study highlights the effectiveness of systematic treatment in managing ONJ with BP-related alterations. Preventative measures, such as regular dental consultations, play a vital role in reducing the risk of ONJ. Multidisciplinary management is essential to addressing the different stages of the condition.

Indexed as

BisphosphonatesBreast cancerMandibleOsteonecrosis

Identifiers

PMID37846293
PMCPMC10577950
OpenAlexW4386378113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.