Evidence map›Paper›PMID 37845755›Full record

ReviewExperimental hematology & oncology2023

Chinese expert consensus on Bruton tyrosine kinase inhibitors in the treatment of B-cell malignancies.

Yuqin Song, Shang-Ju Wu, Zhixiang Shen, Donglu Zhao, Thomas Sau Yan Chan, Huiqiang Huang, Lugui Qiu, Jianyong Li, Tran-der Tan, Jun Zhu and 9 more

Abstract readReview
In one paragraph

Review in Experimental hematology & oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. BTK inhibitors: past, present, and future.Trends in pharmacological sciences · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yuqin SongPeking University Cancer Hospital and Institute, Beijing, China.
Shang-Ju WuHematology Division, Department of Internal Medicine, National Taiwan University Hospital, Taiwan, China.
Zhixiang ShenShanghai Jiaotong University Affiliated Ruijin Hospital, Shanghai, China.
Donglu ZhaoHarbin Hematology and Oncology Institute, Heilongjiang, 150007, China.
Thomas Sau Yan ChanDepartment of Medicine, Queen Mary Hospital, Hong Kong, China.
Huiqiang HuangSun Yat-Sen University Cancer Center, Guangdong, China.
Lugui QiuInstitute of Hematology and Blood Diseases Hospital, Tianjing, China.
Jianyong LiJiangsu Provincial People's Hospital, Jiangsu, China.
Tran-der TanDepartment of Hematology and Medical Oncology, Koo Foundation Sun Yat-Sen Cancer Center, Taiwan, China.
Jun ZhuPeking University Cancer Hospital and Institute, Beijing, China.
Yongping SongThe First Affiliated Hospital of Zhengzhou University, Henan, China.
Wei-Han HuangDepartment of Clinical Pathology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taiwan, China.
Weili ZhaoShanghai Jiaotong University Affiliated Ruijin Hospital, Shanghai, China.
Herman Sung Yu LiuPremier Medical Centre, Hong Kong, China.
Wei XuJiangsu Provincial People's Hospital, Jiangsu, China.
Naizhi ChenMacau Society of Hematology and Oncology, Macau, China.
Jun MaHarbin Hematology and Oncology Institute, Heilongjiang, 150007, China. majun0322@126.com.
Cheng-Shyong ChangDivision of Hematology-Oncology, Department of Internal Medicine, Chang Bing Show Chwan Memorial Hospital, Taiwan, China. cs4816@gmail.com.
Eric Wai Choi TseDepartment of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China. ewctse@hku.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeted therapy with Bruton tyrosine kinase (BTK) inhibitors have revolutionized the treatment of patients with various B-cell malignancies. BTK inhibitors such as ibrutinib, zanubrutinib, orelabrutinib, and acalabrutinib have shown good clinical efficacy and better safety profiles than those of traditional chemotherapy and chemoimmunotherapy regimens. Multiple studies on new BTK inhibitors are ongoing, which may provide more therapeutic options for the treatment of B-cell malignancies. Considering the unmet need of evidence on BTK inhibitors in all clinical settings and to standardize the use of BTK inhibitors available in mainland China, Taiwan, Hong Kong, and Macau regions, this consensus has been formulated for the treatment of various B-cell malignancies based on the clinical practice and available evidences on the use of BTK inhibitors. The recommendations of this consensus will provide guidance to physicians and clinical researchers on the effective treatment of B-cell malignancies with BTK inhibitors.

Indexed as

BTK inhibitorsChinaConsensusNon-Hodgkin lymphomaTargeted therapy

Identifiers

PMID37845755
PMCPMC10578030

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.