Evidence map›Paper›PMID 37845737›Full record

ArticleJournal of biological engineering2023

Novel ultra-stretchable and self-healing crosslinked poly (ethylene oxide)-cationic guar gum hydrogel.

Sergio Alberto Bernal-Chávez, Sergio Alcalá-Alcalá, Zainab M Almarhoon, Aknur Turgumbayeva, Eda Sönmez Gürer, Ma De Los Dolores Campos-Echeverria, Hernán Cortés, Alejandra Romero-Montero, María Luisa Del Prado-Audelo, Javad Sharifi-Rad and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of biological engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 5 countries.

Sergio Alberto Bernal-ChávezDepartamento de Ciencias Químico-Biológicas, Universidad de Las Américas Puebla, Ex-Hda. de Sta. Catarina Mártir, 72820, Puebla, Cholula, Mexico.
Sergio Alcalá-AlcaláLaboratorio de Tecnología Farmacéutica, Facultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, Mexico.
Zainab M AlmarhoonDepartment of Chemistry, College of Science, King Saud University, P. O. Box 2455, 11451, Riyadh, Saudi Arabia.
Aknur TurgumbayevaHigher School of Medicine, Al-Farabi Kazakh National University, Almaty, Kazakhstan.
Eda Sönmez GürerDepartment of Pharmacognosy, Faculty of Pharmacy, Sivas Cumhuriyet University, Sivas, Turkey.
Ma De Los Dolores Campos-EcheverriaDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, 04510, Ciudad de Mexico, Mexico.
Hernán CortésLaboratorio de Medicina Genómica, Departamento de Genómica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, 14389, Ciudad de México, Mexico.
Alejandra Romero-MonteroDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, 04510, Ciudad de Mexico, Mexico.
María Luisa Del Prado-AudeloTecnologico de Monterrey, Campus Ciudad de México, 14380, Ciudad de Mexico, Mexico.
Javad Sharifi-RadFacultad de Medicina, Universidad del Azuay, Cuenca, Ecuador. javad.sharifirad@gmail.com.
Gerardo Leyva-GómezDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, 04510, Ciudad de Mexico, Mexico. leyva@quimica.unam.mx.
Universidad Nacional Autónoma de México · MXAl-Farabi Kazakh National University · KZInstituto Nacional de Rehabilitación · MXKing Saud University · SASivas Cumhuriyet Üniversitesi · TRTecnológico de Monterrey · MXUniversidad Autónoma del Estado de Morelos · MXUniversidad de las Américas Puebla · MXUniversidad del Azuay · EC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogels are three-dimensional structures with specific features that render them useful for biomedical applications, such as tissue engineering scaffolds, drug delivery systems, and wound dressings. In recent years, there has been a significant increase in the search for improved mechanical properties of hydrogels derived from natural products to extend their applications in various fields, and there are different methods to obtain strengthened hydrogels. Cationic guar gum has physicochemical properties that allow it to interact with other polymers and generate hydrogels. This study aimed to develop an ultra-stretchable and self-healing hydrogel, evaluating the influence of adding PolyOX [poly(ethylene oxide)] on the mechanical properties and the interaction with cationic guar gum for potential tissue engineering applications. We found that variations in PolyOX concentrations and pH changes influenced the mechanical properties of cationic guar gum hydrogels. After optimization experiments, we obtained a novel hydrogel, which was semi-crystalline, highly stretchable, and with an extensibility area of approximately 400 cm

Indexed as

Cationic guar gumHydrogelPoly(ethylene oxide)Soft tissuesTissue engineeringWounds

Identifiers

PMID37845737
PMCPMC10577977
OpenAlexW4387668633

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.