Evidence map›Paper›PMID 37845676›Full record

SynthesisBMC psychiatry2023

A meta-analysis on the therapeutic efficacy of repetitive transcranial magnetic stimulation for cognitive functions in attention-deficit/hyperactivity disorders.

Ying-Hsin Chen, Shun-Chin Liang, Cheuk-Kwan Sun, Yu-Shian Cheng, Ruu-Fen Tzang, Hsien-Jane Chiu, Ming-Yu Wang, Ying-Chih Cheng, Kuo-Chuan Hung

Registry-linked trialOpen access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07182344 (Effects of iTBS on Cognitive Control in Children With ADHD), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07182344 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Effects of iTBS on Cognitive Control in Children With ADHD: A Randomized, Sham-Controlled Study Integrating EEG During ANT, fNIRS, MRI, and Genetic Markers

TypeinterventionalSponsorNeurolab PlusRan2025 to 2026Enrolled40ConditionsADHD - Attention Deficit Disorder With HyperactivityArmsIntermittent Theta Burst Stimulation to Right DLPFC, Sham Intermittent Theta Burst Stimulation
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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  6. Enhancing working memory in MCI: Modulating alpha-gamma coupling and gamma oscillations via rTMS.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Ying-Hsin Chen *Department of Emergency Medicine, Show Chwan Memorial Hospital, Changhua, Taiwan.
Shun-Chin Liang *Department of Management Center, Jianan Psychiatric Center, Ministry Of Health and Welfare, Tainan, Taiwan.
Cheuk-Kwan Sun *Department of Emergency Medicine, E-Da Dachang Hospital, I-Shou University, Kaohsiung City, Taiwan.
Yu-Shian ChengDepartment of Psychiatry, Tsyr-Huey Mental Hospital, Kaohsiung Jen-Ai's Home, Kaohsiung City, Taiwan.
Ruu-Fen TzangDepartment of Psychiatry, Mackay Memorial Hospital, Taipei City, Taiwan.
Hsien-Jane ChiuTaoyuan Psychiatric Center, Ministry of Health and Welfare, Taoyuan City, Taiwan.
Ming-Yu WangDepartment of Psychiatry, China Medical University Hsinchu Hospital, China Medical University, Hsinchu, Taiwan.
Ying-Chih ChengDepartment of Psychiatry, China Medical University Hsinchu Hospital, China Medical University, Hsinchu, Taiwan.
Kuo-Chuan HungDepartment of Anesthesiology, Chi Mei Medical Center, Tainan City, Taiwan. ed102605@gmail.com.
China Medical University Hospital · TWChang Bing Show Chwan Memorial Hospital · TWChi Mei Medical Center · TWChung Hwa University of Medical Technology · TWI-Shou University · TWMackay Memorial Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTherapeutic efficacies of repetitive transcranial magnetic stimulation (rTMS) for improving cognitive functions in patients with deficit/hyperactivity disorder (ADHD) remained unclear. The aim of this meta-analysis was to investigate the therapeutic efficacy of rTMS focusing on different cognitive performances.

methodsMajor databases were searched electronically from inception to February 2023 by using keywords mainly "rTMS" and "ADHD" to identify randomized controlled trials (RCTs) that investigated the therapeutic efficacy of rTMS for improving cognitive functions assessed by standardized tasks in patients with ADHD. The overall effect size (ES) was calculated as standardized mean difference (SMD) based on a random effects model.

resultsMeta-analysis of five RCTs with 189 participants (mean age of 32.78 and 8.53 years in adult and child/adolescent populations, respectively) demonstrated that rTMS was more effective for improving sustained attention in patients with ADHD compared with the control groups (SMD = 0.54, p = 0.001).Our secondary analysis also showed that rTMS was more effective for improving processing speed than the control groups (SMD = 0.59, p = 0.002) but not for enhancing memory or executive function.

conclusionsOur results supported the therapeutic efficacy of rTMS for improving sustained attention and processing speed. However, the limitation of available data warrants further studies to verify these findings.

Indexed as

Attention Deficit Disorder with HyperactivityTranscranial Magnetic StimulationAdolescentAdultChildCognitionExecutive FunctionHumansProcessing SpeedAnd cognitive functionsAttention-deficit/hyperactivity disorderRepetitive transcranial magnetic stimulation

Identifiers

PMID37845676
PMCPMC10580630
OpenAlexW4387664274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.