Evidence map›Paper›PMID 37845615›Full record

ArticleBMC pediatrics2023

Relationship between gut microbiota dysbiosis and immune indicator in children with sepsis.

Xia Lin, Mohnad Abdalla, Junjie Yang, Lei Liu, Yali Fu, Yanli Zhang, Shuchun Yang, Han Yu, Yongsheng Ge, Sufang Zhang and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Higher abundance ofmSystems · 2026
    Article
  3. Article
  4. Gut microbes · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Xia LinChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Mohnad AbdallaChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Junjie YangCollege of Life Science, Qilu Normal University, Jinan, Shandong, 250200, China.
Lei LiuChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Yali FuChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Yanli ZhangChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Shuchun YangChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Han YuChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Yongsheng GeChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Sufang ZhangChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Guiyun KangChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Wei DangChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Qin JiangChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China. doctorjiang1994@163.com.
Ying WangChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China. wangyingying67@163.com.
Zhongtao GaiChildren's Hospital Affiliated to Shandong University, Jinan, 250022, China.
Shandong University · CNQilu Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is a life-threatening multiple-organ injury caused by disordered host immune response to microbial infection. However, the correlation between gut microbiota dysbiosis and immune indicators remains unexplored. To address this gap in knowledge, we carried out 16 S rDNA sequencing, analyzed clinical fecal samples from children with sepsis (n = 30) and control children (n = 25), and obtained immune indicators, including T cell subtypes (CD3

Indexed as

Gastrointestinal MicrobiomeSepsisBacteriaBiomarkersCD8-Positive T-LymphocytesChildDysbiosisHumansImmunoglobulin MInterleukin-4BiomarkersImmunoglobulin MInterleukin-4BiomarkerChildrenGut microbiotaImmune indicatorsepsis

Identifiers

PMID37845615
PMCPMC10578006
OpenAlexW4387672353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.