Evidence map›Paper›PMID 37845561›Full record

ArticleImmunologic research2024

Palpitation in women with silicone breast implants: association with autoantibodies against autonomic nervous system.

Tal Elroy, Gilad Halpert, Avishai M Tsur, Harald Heidecke, Howard Amital, Yehuda Shoenfeld

Abstract read
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In one paragraph

Article in Immunologic research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Tal ElroySackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. elroytal@gmail.com.ORCID 0009-0001-2633-8320
Gilad HalpertZabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, 52621, Ramat-Gan, Israel.
Avishai M TsurDepartment of Medicine 'B' and Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Ramat-Gan, Israel.
Harald HeideckeCellTrend GmbH, Luckenwalde, Germany.
Howard AmitalSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Yehuda ShoenfeldZabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, 52621, Ramat-Gan, Israel.
Sheba Medical Center · ILTel Aviv University · ILHebrew University of Jerusalem · ILInstitute of Pathology Celle · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We explored a possible association between palpitation manifestation in women with silicone breast implants (SBIs) with circulating level of autoantibodies directed against autonomic nervous system (ANS) receptors. The study was conducted in 93 women with SBIs who arrived to our clinic with diverse symptoms thought to be associated with their implants. Titers of 11 various autoantibodies were measured in the sera of women with SBIs who experienced palpitations (Palpitations, n = 47), did not experience palpitations (Non, n = 46), and healthy women (Control, n = 36). A significant reduction in anti-α2-adrenergic receptor (A2AR, P = 0.035), anti-β2-adrenergic receptor (B2AR, P = 0.027), antimuscarinic receptors M1R (P = 0.048), and anti-M2R (P = 0.039) autoantibodies was found in the 'Palpitations' group as compared with the 'Non' group. Anti-B2AR (P = 0.042), anti-M1R (P = 0.017), and anti-M2R (P = 0.0015) autoantibodies were also significantly reduced in 'Palpitations' as compared with the 'Control' group. Our study shows possible association between autoantibodies directed against ANS receptors, with existing complaints of palpitations in women with SBIs.

Indexed as

AutoantibodiesBreast ImplantsFemaleHumansReceptors, AdrenergicSiliconesAutoantibodiesReceptors, AdrenergicSiliconesAdrenergic receptorsAutoantibodiesAutoimmune diseaseAutoimmune Syndrome Induced by Adjuvants (ASIA)AutoimmunityAutonomic nervous systemG protein-coupled receptors (GPCR)Muscarinic receptorsPalpitationsSilicone breast implants

Identifiers

PMID37845561
OpenAlexW4387666066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.