Evidence map›Paper›PMID 37845428›Full record

ArticleJournal of molecular neuroscience : MN2023

Assessment of tRNA

Dhivya Venkatesan, Mahalaxmi Iyer, Neethu Raj, Abilash Valsala Gopalakrishnan, Arul Narayanasamy, Nachimuthu Senthil Kumar, Balachandar Vellingiri

Abstract read
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In one paragraph

Article in Journal of molecular neuroscience : MN, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Mitochondrial tRNA-Derived Diseases.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Dhivya VenkatesanHuman Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, 641 046, Tamil Nadu, India.
Mahalaxmi IyerCentre for Neuroscience, Department of Biotechnology, Karpagam Academy of Higher Education (Deemed to be University), Coimbatore, 641021, India.
Neethu RajHuman Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, 641 046, Tamil Nadu, India.
Abilash Valsala GopalakrishnanDepartment of Biomedical Sciences, School of Biosciences and Technology, Vellore Institute of Technology, Vellore, 632 014, India.
Arul NarayanasamyDisease Proteomics Laboratory, Department of Zoology, Bharathiar University, Coimbatore, 641 046, Tamil Nadu, India.
Nachimuthu Senthil KumarDepartment of Biotechnology, Mizoram University, Aizawl, Mizoram, 796004, India.
Balachandar VellingiriHuman Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, 641 046, Tamil Nadu, India. balachandar.vellingiri@cup.edu.in.
Bharathiar University · INKarpagam Academy of Higher Education · INCentral University of Punjab · INMizoram University · INVellore Institute of Technology University · IN

Funding

Indian Council of Medical Research 45/2/2018-Hum/BMS
6 · The paper itself

Abstract

Parkinson's disease (PD) is speculated with genetic and environmental factors. At molecular level, the mitochondrial impact is stated to be one of the causative reasons for PD. In this study, we investigated the mitochondrial membrane potential (MMP), reactive oxygen species (ROS) and adenosine triphosphate (ATP) levels along with mitochondrial tRNA alterations among three age categories of PD. By determining the genetic and organellar functionality using molecular techniques, the ROS levels were reported to be high with decreased MMP and ATP in the late-onset age group than in other two age categories. Likewise, the tRNA significancy in tRNA

Indexed as

Parkinson DiseaseRNA, Transfer, ThrAdenosine TriphosphateHumansIndiaMitochondriaReactive Oxygen SpeciesRNA, Transfer, GlnAdenosine TriphosphateReactive Oxygen SpeciesRNA, Transfer, GlnRNA, Transfer, ThrAdenosine triphosphate (ATP)AgeingMitochondrial membrane potential (MMP)Parkinson’s disease (PD)Reactive oxygen species (ROS)tRNA

Identifiers

PMID37845428
OpenAlexW4387662515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.