Evidence map›Paper›PMID 37845033›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Complex Synaptic and Intrinsic Interactions Disrupt Input/Output Functions in the Hippocampus of

Jessica Hotard Chancey, Alisha A Ahmed, Fernando Isaac Guillén, Vighnesh Ghatpande, MacKenzie A Howard

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. A Novel Mouse Model for Developmental and Epileptic Encephalopathy by Purkinje Cell-Specific Deletion ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jessica Hotard ChanceyDepartments of Neurology and Neuroscience, Center for Learning and Memory, Dell Medical School, University of Texas at Austin, Austin, Texas 78712.ORCID 0000-0002-8807-3938
Alisha A AhmedDepartments of Neurology and Neuroscience, Center for Learning and Memory, Dell Medical School, University of Texas at Austin, Austin, Texas 78712.
Fernando Isaac GuillénDepartments of Neurology and Neuroscience, Center for Learning and Memory, Dell Medical School, University of Texas at Austin, Austin, Texas 78712.
Vighnesh GhatpandeDepartments of Neurology and Neuroscience, Center for Learning and Memory, Dell Medical School, University of Texas at Austin, Austin, Texas 78712.
MacKenzie A HowardDepartments of Neurology and Neuroscience, Center for Learning and Memory, Dell Medical School, University of Texas at Austin, Austin, Texas 78712 mackenziehoward@austin.utexas.edu.ORCID 0000-0003-2832-6873
The University of Texas at Austin · US

Funding

Mechanisms of altered synaptic integration and plasticity underlying cellular and circuit dysfunction in genetic epilepsy disordersR01NS112500 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI HOWARD, MACKENZIE A · 2020 to 2024
$1.8M
NINDS NIH HHS R01 NS112500
6 · The paper itself

Abstract

Pathogenic variants in

Indexed as

Epilepsies, MyoclonicEpilepsyAnimalsFemaleHippocampusHumansMaleMiceMice, KnockoutParvalbuminsPyramidal CellsSeizuresVoltage-Gated Sodium Channel beta-1 SubunitParvalbuminsScn1b protein, mouseVoltage-Gated Sodium Channel beta-1 SubunitDravet syndromeencephalopathyepilepsyplasticitySCN1Bsynaptic integration

Identifiers

PMID37845033
PMCPMC10711733
OpenAlexW4387665692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.