Evidence map›Paper›PMID 37844221›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Functional genomic diversity is correlated with neutral genomic diversity in populations of an endangered rattlesnake.

Samarth Mathur, Andrew J Mason, Gideon S Bradburd, H Lisle Gibbs

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
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  7. Methylation-associated mutagenesis underlies variation in the mutation spectrum across eukaryotes.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  9. Review
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  15. Inbreeding reduces fitness in spatially structured populations of a threatened rattlesnake.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
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  18. Natural dispersal is better than translocation for reducing risks of inbreeding depression in eastern black rhinoceros (Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Samarth MathurDepartment of Evolution, Ecology, and Organismal Biology, The Ohio State University, Columbus, OH 48824.ORCID 0000-0002-6446-5718
Andrew J MasonDepartment of Evolution, Ecology, and Organismal Biology, The Ohio State University, Columbus, OH 48824.ORCID 0000-0003-0297-1313
Gideon S BradburdEvolution and Behavior Program, Department of Integrative Biology, Ecology, Michigan State University, East Lansing, MI 48824.
H Lisle GibbsDepartment of Evolution, Ecology, and Organismal Biology, The Ohio State University, Columbus, OH 48824.ORCID 0000-0001-7461-3393
The Ohio State University · USUniversity of Michigan · US

Funding

Incorporating geography into statistical methods for analysis of population genomic DNAR35GM137919 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gideon Bradburd · 2020 to 2026
$2.3M
NIGMS NIH HHS R35 GM137919NIGMS NIH HHS R35GM137919
6 · The paper itself

Abstract

Theory predicts that genetic erosion in small, isolated populations of endangered species can be assessed using estimates of neutral genetic variation, yet this widely used approach has recently been questioned in the genomics era. Here, we leverage a chromosome-level genome assembly of an endangered rattlesnake (

Indexed as

CrotalusGenetic VariationAnimalsEndangered SpeciesGenomeGenomicsHumansInbreedingadaptive variationconservation genomicsmutation loadneutral and functional genomic diversitySistrurus catenatus

Identifiers

PMID37844221
PMCPMC10614936
OpenAlexW4387665104

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.