Evidence map›Paper›PMID 37844030›Full record

ArticleVascular medicine (London, England)2024

National survey of patient symptoms and therapies among 707 women with a lipedema phenotype in the United States.

Aaron W Aday, Paula Mc Donahue, Maria Garza, Vanessa N Crain, Niral J Patel, John A Beasley, Karen L Herbst, Joshua A Beckman, Shannon L Taylor, Michael Pridmore and 3 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Vascular medicine (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07603076 (Evaluation of Venous Insufficiency and Its Association With Clinical Features in Patients With Lipedema), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07603076 recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of Venous Insufficiency and Its Association With Clinical Features in Patients With Lipedema: A Cross-Sectional Study

TypeobservationalSponsorSultan Abdulhamid Han Training and Research Hospital, Istanbul, TurkeyRan2026 to 2026Enrolled82ConditionsLipedema, Venous Insufficiency, Venous Disease, Disability PhysicalArmsVenous Doppler Ultrasonography, Numeric Rating Scale, Lower Extremity Functional Scale, Short Form-12, Lower Extremity Circumference at Standardized Anatomical Landmarks (cm)
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Vascular changes and their implications in lipedema.Frontiers in cell and developmental biology · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Aaron W AdayDivision of Cardiovascular Medicine, Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-6243-3432
Paula Mc DonahueDepartment of Physical Medicine and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA.
Maria GarzaDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
Vanessa N CrainDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Niral J PatelDepartment of Pediatrics, Division of Pediatric Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
John A BeasleyDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Karen L HerbstTotal Lipedema Care, Beverly Hills, CA and Tucson, AZ, USA.
Joshua A BeckmanDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-8332-8439
Shannon L TaylorDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Michael PridmoreDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Sheau-Chiann ChenDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Manus J DonahueDepartment of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA.
Rachelle CrescenziDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Vanderbilt University Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Postdoctoral Training in Biomedical MRI and MRST32EB001628 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John C Gore · 2003 to 2026
$7.0M
Visualizing vascular mechanisms of lipedemaR01HL157378 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CRESCENZI, RACHELLE L · 2021 to 2025
$2.5M
The Impact of Thrombosis and Antithrombotic Therapy on Peripheral Artery DiseaseK23HL151871 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ADAY, AARON W. · 2021 to 2025
$927k
NCATS NIH HHS UL1 TR002243NHLBI NIH HHS K23 HL151871NHLBI NIH HHS R01 HL157378NIBIB NIH HHS T32 EB001628
6 · The paper itself

Abstract

backgroundNational survey data exploring the patient experience with lipedema are lacking.

methodsWe conducted national surveys from 2016 to 2022 of women with lipedema as well as female controls. Surveys collected information on symptomatology, pain, and therapies. We performed logistic regression comparing symptoms among those with lipedema versus controls adjusting for age and BMI.

resultsA total of 707 women with lipedema and 216 controls completed the surveys. Those with lipedema had a mean age of 48.6 years and mean BMI of 40.9 kg/m

conclusionIn a large, national, symptom survey, women with lipedema reported excess pain, swelling, and fat in the legs along with numerous symptoms beyond those classically described. Symptom responses to common therapies remain understudied.

Indexed as

LipedemaEdemaFemaleHumansLegMiddle AgedPainPhenotypePregnancyUnited Statesleg swellinglipedemalipoedemaobesityquality of lifesurveys

Identifiers

PMID37844030
PMCPMC10858625
OpenAlexW4387674309

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.