Evidence map›Paper›PMID 37843805›Full record

ArticleAdvances in experimental medicine and biology2023

Unveiling Microbial Chemical Interactions Based on Metabolomics Approaches.

Laís Castro de Carvalho, Arnaldo de Almeida Junior, Fernanda Silva Ribeiro, Célio Fernando Figueiredo Angolini

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In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laís Castro de CarvalhoMass Spectrometry and Chemical Ecology Laboratory (MC-CELL), Center for Natural and Human Sciences, University of ABC (UFABC), São Paulo, Brazil.
Arnaldo de Almeida JuniorMass Spectrometry and Chemical Ecology Laboratory (MC-CELL), Center for Natural and Human Sciences, University of ABC (UFABC), São Paulo, Brazil.
Fernanda Silva RibeiroMass Spectrometry and Chemical Ecology Laboratory (MC-CELL), Center for Natural and Human Sciences, University of ABC (UFABC), São Paulo, Brazil.
Célio Fernando Figueiredo AngoliniMass Spectrometry and Chemical Ecology Laboratory (MC-CELL), Center for Natural and Human Sciences, University of ABC (UFABC), São Paulo, Brazil. celio.fernando@ufabc.edu.br.
Universidade Federal do ABC · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microorganisms are ubiquitous in diverse habitats and studying their chemical interactions with the environment and comprehend its complex relations with both hosts and environment, are crucial for the development of strategies to control microbial diseases. This chapter discusses the importance of studying microorganisms with agricultural benefits, using specialized metabolites as examples. Herein we highlight the challenges and opportunities in utilizing microorganisms as alternatives to synthetic pesticides and fertilizers in agriculture. Genome-guided investigations and improved analytical methodologies are necessary to characterize diverse and complex biomolecules produced by microorganisms. Predicting and isolating bioproducts based on genetic information have become a focus for researchers, aided by tools like antiSMASH, BiG-SCAPE, PRISM, and others. However, translating genomic data into practical applications can be complex. Therefore, integrating genomics, transcriptomics, and metabolomics enhances chemical characterization, aiding in discovering new metabolic pathways and specialized metabolites. Additionally, elicitation is one promising strategy to enhance beneficial metabolite production. Finally, identify and characterize microbial secondary metabolites remain challenging due to their low production, complex chemical structure characterization and different environmental factors necessary for metabolite in vitro production.

Indexed as

MetabolomicsPesticidesGene Expression ProfilingGenomicsMetabolic Networks and PathwaysPesticidesChemical elicitationGenomicsMass spectrometryMetabolomicsMicrobial chemical ecologySpecialized metabolites

Identifiers

PMID37843805
OpenAlexW4387661067

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.