Evidence map›Paper›PMID 37843767›Full record

ArticlePhysical and engineering sciences in medicine2024

The assessment of the clinical impact of using a single set of radiotherapy planning data for two kilovoltage therapy units.

Iliana Peters, Vinod Nelson, Shrikant Deshpande, Amy Walker, Joshua Hiatt, Dale Roach, Tania Erven, Satya Rajapakse, Alison Gray

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Article in Physical and engineering sciences in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Iliana PetersSouth Western Sydney Local Health District, Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia. iliana.peters@health.nsw.gov.au.ORCID http://orcid.org/0000-0001-7570-1416
Vinod NelsonSouth Western Sydney Local Health District, Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia.
Shrikant DeshpandeSouth Western Sydney Local Health District, Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia.
Amy WalkerSouth Western Sydney Local Health District, Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia.
Joshua HiattSouth Western Sydney Local Health District, Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia.
Dale RoachSouth Western Sydney Local Health District, Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia.
Tania ErvenSouth Western Sydney Local Health District, Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia.
Satya RajapakseSouth Western Sydney Local Health District, Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia.
Alison GraySouth Western Sydney Local Health District, Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kilovoltage therapy units are used for superficial radiotherapy treatment delivery. Peer reviewed studies for MV linear accelerators describe tolerances to dosimetrically match multiple linear accelerators enabling patient treatment on any matched machine. There is an absence of literature on using a single planning data set for multiple kilovoltage units which have limited ability for beam adjustment. This study reviewed kilovoltage dosimetry and treatment planning scenarios to evaluate the feasibility of using ACPSEM annual QA tolerances to determine whether two units (of the same make and model) were dosimetrically matched. The dosimetric characteristics, such as measured half value layer (HVL), percentage depth dose (PDD), applicator factor and output variation with stand-off distance for each kV unit were compared to assess the agreement. Independent planning data based on the measured HVL for each beam energy from each kV unit was prepared. Monitor unit (MU) calculations were performed using both sets of planning data for approximately 200 clinical scenarios and compared with an overall agreement between units of < 2%. Additionally, a dosimetry measurement comparison was completed at each site for a subset of nine scenarios. All machine characterisation measurements were within the ACPSEM Annual QA tolerances, and dosimetric testing was within 2.5%. This work demonstrates that using a single set of planning data for two kilovoltage units is feasible, resulting in a clinical impact within published uncertainty.

Indexed as

RadiometryRadiotherapy Planning, Computer-AssistedHumansParticle AcceleratorsPhantoms, ImagingUncertaintyKilovoltage therapyMatching kilovoltage unitsPlanning dataRadiation oncologyUncertainty

Identifiers

PMID37843767

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.