Evidence map›Paper›PMID 37843699›Full record

ArticleJournal of molecular histology2023

Serum HBV RNA levels among untreated adults with chronic hepatitis B in distinct immune phases and liver histopathology statuses.

Qin Xu, Hai Ding, Tao Bai, Rui Huang, Jian Wang, Jun Zhang, Hewei Luan, Jun Wang, Yue Yang, Yuxin Chen

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular histology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Qin Xu *Department of Laboratory Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Hai Ding *Department of Laboratory Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Tao Bai *Department of Infectious Diseases, Wuhan Jinyintan Hospital, Hubei Clinical Research Center for Infectious Diseases, Tongji Medical College of Huazhong University of Science and Technology, Hubei, China.
Rui HuangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Jian WangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Jun ZhangDepartment of Laboratory Medicine, Jurong Hospital Affiliated to Jiangsu University, Jurong, China.
Hewei LuanDepartment of Laboratory Medicine, Jurong Hospital Affiliated to Jiangsu University, Jurong, China.
Jun WangDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China. wjlh9999@sina.com.
Yue YangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. xiluoyike@163.com.
Yuxin ChenDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China. yuxin.chen@nju.edu.cn.
Jiangsu University · CNNanjing Drum Tower Hospital · CNNanjing Medical University · CNJinyintan Hospital · CNNanjing University · CN

Funding

Clinical Trials from the Affiliated Drum Tower Hospital, Medical School of Nanjing University 2021-LCYJ-PY-09Scientific Research Project of Jiangsu Health Commission M2022013Training Program of the Major Research Plan of the National Natural Science Foundation of China 92269118Training Program of the Major Research Plan of the National Natural Science Foundation of China 92269205
6 · The paper itself

Abstract

HBV RNA is a novel serum biomarker that reflects intrahepatic HBV covalently closed circular DNA (cccDNA) transcription activity. Serum HBV RNA levels among treatment-naïve adults during the natural history of chronic hepatitis B (CHB) and distinct liver histopathology statuses remain elusive. In our study, we include a total of 411 treatment-naïve CHB patients, among which 43 patients were HBeAg-positive immune-tolerant [IT(e

Indexed as

Hepatitis B, ChronicHepatitis B virusAdultDNA, ViralHepatitis B e AntigensHumansInflammationLiverLiver CirrhosisRNADNA, ViralHepatitis B e AntigensRNAChronic hepatitis BHBV RNAHepatitis B virusLiver histopathology

Identifiers

PMID37843699
OpenAlexW4387661812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.