Evidence map›Paper›PMID 37843644›Full record

ArticleWorld journal of microbiology & biotechnology2023

Evaluating the potential of semi-continuous itaconic acid fermentation by Aspergillus terreus: operational profile and experiences.

Éva Hülber-Beyer, Katalin Bélafi-Bakó, Tamás Rózsenberszki, Péter Komáromy, Nándor Nemestóthy

Abstract read
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In one paragraph

Article in World journal of microbiology & biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Éva Hülber-BeyerResearch Group on Bioengineering, Membrane Technology and Energetics, Faculty of Engineering, University of Pannonia, Egyetem str. 10, Veszprém, 8200, Hungary. beyer.eva@mk.uni-pannon.hu.ORCID http://orcid.org/0000-0002-9052-4507
Katalin Bélafi-BakóResearch Group on Bioengineering, Membrane Technology and Energetics, Faculty of Engineering, University of Pannonia, Egyetem str. 10, Veszprém, 8200, Hungary.ORCID http://orcid.org/0000-0003-4702-5857
Tamás RózsenberszkiResearch Group on Bioengineering, Membrane Technology and Energetics, Faculty of Engineering, University of Pannonia, Egyetem str. 10, Veszprém, 8200, Hungary.ORCID http://orcid.org/0000-0002-0799-7128
Péter KomáromyResearch Group on Bioengineering, Membrane Technology and Energetics, Faculty of Engineering, University of Pannonia, Egyetem str. 10, Veszprém, 8200, Hungary.ORCID http://orcid.org/0000-0002-4203-0449
Nándor NemestóthyResearch Group on Bioengineering, Membrane Technology and Energetics, Faculty of Engineering, University of Pannonia, Egyetem str. 10, Veszprém, 8200, Hungary.ORCID http://orcid.org/0000-0001-6983-5223

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Itaconic acid is an important bio-based chemical. The present study aims to evaluate the applicability of semi-continuous fermentation technique for itaconic acid production by Aspergillus terreus. The fermentation is planned to be connected with bipolar membrane electrodialysis unit for acid recovery. This process allows the reuse of residual glucose from the effluent. Our particular attention was focused on the effect of glucose concentration. Two different glucose supplementation strategies were tested: constant glucose concentration in the refilling medium and adjusted glucose concentration in order to maintain a continuously high - 120 g/L - glucose concentration in the fermentor. The itaconic acid titre, yield and productivity for the 24 h time periods between draining/refilling interventions were investigated. The constantly high glucose concentration in the fermentor resulted in doubled biomass formation. The average itaconic acid titre was 32.9 ± 2.7 g/L. The producing strain formed numerous spores during semi-continuous fermentation that germinated continuously. Yield and volumetric productivity showed a periodic pattern during the procedure.

Indexed as

AspergillusSuccinatesFermentationGlucoseGlucoseitaconic acidSuccinatesAccessory conidiumAspergillus terreusItaconic acidSemi-continuous fermentation

Identifiers

PMID37843644
PMCPMC10579124

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.