Evidence map›Paper›PMID 37843642›Full record

ReviewNatural products and bioprospecting2023

Exploring the role of natural bioactive molecules in genitourinary cancers: how far has research progressed?

Fahadul Islam, Nikhil Nath, Mehrukh Zehravi, Jishan Khan, Sumiya Ben-Ta Jashim, Manoj Shrawan Charde, Rita Dadarao Chakole, K Praveen Kumar, A Kishore Babu, Firzan Nainu and 4 more

Open access · diamondAbstract readReview
In one paragraph

Review in Natural products and bioprospecting, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 6 countries.

Fahadul Islam *Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, 1207, Bangladesh.
Nikhil NathDepartment of Pharmacy, International Islamic University Chittagong, Kumira, Chittagong, 4318, Bangladesh.
Mehrukh Zehravi *Department of Clinical Pharmacy, College of Dentistry & Pharmacy, Buraydah Private Colleges, Buraydah, 51418, Kingdom of Saudi Arabia. mahrukh.zehravi@hotmail.com.
Jishan KhanDepartment of Pharmacy, International Islamic University Chittagong, Kumira, Chittagong, 4318, Bangladesh.
Sumiya Ben-Ta JashimDepartment of Pharmacy, International Islamic University Chittagong, Kumira, Chittagong, 4318, Bangladesh.
Manoj Shrawan ChardeGovernment College of Pharmacy, Vidyanagar, Karad, Satara, 415124, Maharashtra, India.
Rita Dadarao ChakoleGovernment College of Pharmacy, Vidyanagar, Karad, Satara, 415124, Maharashtra, India.
K Praveen KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Govt. of NCT of Delhi, Delhi Pharmaceutical Sciences and Research University (DPSRU), Mehrauli-Badarpur Road, PushpVihar, Sector 3, New Delhi, 110017, India.
A Kishore BabuRatnadeep College of Pharmacy, Ratnapur, Jamkhed, Ahmednagar, 413206, Maharashtra, India.
Firzan NainuDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, 90245, Indonesia.
Sharuk L KhanDepartment of Pharmaceutical Chemistry, N.B.S. Institute of Pharmacy, Ausa, 413520, Maharashtra, India.
Safia Obaidur RabDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Talha Bin EmranDepartment of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, 1207, Bangladesh. talhabmb@bgctub.ac.bd.ORCID http://orcid.org/0000-0003-3188-2272
Polrat Wilairatana *Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand. polrat.wil@mahidol.ac.th.
International Islamic University Chittagong · BDDaffodil International University · BDBuraydah Colleges · SADelhi Pharmaceutical Science and Research University · INHasanuddin University · IDKing Khalid University · SAMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary approaches to treat cancerous diseases include drug treatment, surgical procedures, biotherapy, and radiation therapy. Chemotherapy has been the primary treatment for cancer for a long time, but its main drawback is that it kills cancerous cells along with healthy ones, leading to deadly adverse health effects. However, genitourinary cancer has become a concern in recent years as it is more common in middle-aged people. So, researchers are trying to find possible therapeutic options from natural small molecules due to the many drawbacks associated with chemotherapy and other radiation-based therapies. Plenty of research was conducted regarding genitourinary cancer to determine the promising role of natural small molecules. So, this review focused on natural small molecules along with their potential therapeutic targets in the case of genitourinary cancers such as prostate cancer, renal cancer, bladder cancer, testicular cancer, and so on. Also, this review states some ongoing or completed clinical evidence in this regard.

Indexed as

ApoptosisChemotherapyGenitourinary cancersPolyphenolsUrinary tract

Identifiers

PMID37843642
PMCPMC10579213
OpenAlexW4387661444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.