Evidence map›Paper›PMID 37843575›Full record

ArticleOrthopadie (Heidelberg, Germany)2023

[Platelet-rich plasma (PRP) : Compositional analysis with different dietary habits and timing of blood sampling].

Hadrian Platzer, Kristina Dorothea Kubon, Solvig Diederichs, Alena Bork, Simone Gantz, Marcus Schiltenwolf, Tobias Renkawitz, Yannic Bangert

Open access · hybridAbstract readEnglish Abstract
In one paragraph

Article in Orthopadie (Heidelberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Platelet-rich Plasma: ACurrent drug research reviews · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hadrian PlatzerOrthopädische Universitätsklinik Heidelberg, Ruprecht-Karls-Universität, Schlierbacher Landstraße 200a, 69118, Heidelberg, Deutschland.
Kristina Dorothea KubonOrthopädische Universitätsklinik Heidelberg, Ruprecht-Karls-Universität, Schlierbacher Landstraße 200a, 69118, Heidelberg, Deutschland.
Solvig DiederichsOrthopädische Universitätsklinik Heidelberg, Ruprecht-Karls-Universität, Schlierbacher Landstraße 200a, 69118, Heidelberg, Deutschland.
Alena BorkOrthopädische Universitätsklinik Heidelberg, Ruprecht-Karls-Universität, Schlierbacher Landstraße 200a, 69118, Heidelberg, Deutschland.
Simone GantzOrthopädische Universitätsklinik Heidelberg, Ruprecht-Karls-Universität, Schlierbacher Landstraße 200a, 69118, Heidelberg, Deutschland.
Marcus SchiltenwolfOrthopädische Universitätsklinik Heidelberg, Ruprecht-Karls-Universität, Schlierbacher Landstraße 200a, 69118, Heidelberg, Deutschland.
Tobias RenkawitzOrthopädische Universitätsklinik Heidelberg, Ruprecht-Karls-Universität, Schlierbacher Landstraße 200a, 69118, Heidelberg, Deutschland.
Yannic BangertOrthopädische Universitätsklinik Heidelberg, Ruprecht-Karls-Universität, Schlierbacher Landstraße 200a, 69118, Heidelberg, Deutschland. yannic.bangert@med.uni-heidelberg.de.
Orthopädische Universitätsklinik · DEHeidelberg University · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The variability of PRP is a major contributor to the lack of evidence regarding the therapeutic effect of PRP in musculoskeletal diseases. In a large study, we are currently investigating factors that may influence PRP variability. Interim results showed that concentrations of IL‑6, but not IGF‑1 or cellular constituents, were significantly decreased in PRP samples from vegans compared with omnivores and tended to be decreased compared to samples from vegetarians. This suggests that diet may have a significant influence on therapeutically active PRP constituents. However, the constituents studied here did not appear to be significantly affected by the timing of the sampling. Identification of significant variables affecting PRP composition will be critical to provide sufficient medical evidence for the therapeutic effects of PRP in orthopedic conditions.

Indexed as

Musculoskeletal DiseasesPlatelet-Rich PlasmaHumansSpecimen HandlingVascular Endothelial Growth Factor AVascular Endothelial Growth Factor ACircadian rhythmInsulin like growth factor IInterleukin‑6OsteoarthritisThrombocytes

Identifiers

PMID37843575
PMCPMC10622356
OpenAlexW4387662062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.