ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2024
Intraocular pressure spikes after gonioscopy-assisted transluminal trabeculotomy (GATT).
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Intraocular pressure spikes after trabecular meshwork strip peeling during hemi-GATT.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Comparing combined trabeculotomy-trabeculectomy with gonioscopy-assisted transluminal trabeculotomy as primary surgery for primary congenital glaucoma.Indian journal of ophthalmology · 2026Article
- Comparison of outcomes of circumferential versus hemi-gonioscopy-assisted transluminal trabeculotomy in primary open-angle glaucoma: 24-Month results.International ophthalmology · 2026Article
- Two-year clinical outcomes of standalone gonioscopy-assisted transluminal trabeculotomy in normal-tension glaucoma.Frontiers in medicine · 2026Article
- Ab interno trabeculotomy with vs. without cataract surgery for POAG: a retrospective study.Frontiers in medicine · 2026Article
- Insights into intraocular pressure spikes following gonioscopy-assisted transluminal trabeculotomy (GATT): timing, predictors and clinical outcomes.Japanese journal of ophthalmology · 2026Observational
- A Systematic and Narrative Review of Safety and Complications in Minimally Invasive Glaucoma Surgery (MIGS) Between 2014-2024.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Efficacy and safety of 360º and 180º gonioscopy-assisted transluminal trabeculotomy in combination with phacoemulsification in patients with open-angle glaucoma: a retrospective case-control study.BMC ophthalmology · 2025Article
- Incidence and risk factors for early transient intraocular pressure elevation after penetrating canaloplasty in patients with glaucoma.BMC ophthalmology · 2025Article
- Analysis of surgical outcomes and risk factors after gonioscopy-assisted transluminal trabeculotomy.BMC ophthalmology · 2025Observational
- Ab Interno Goniotomy/Goniectomy TechniquesTurkish journal of ophthalmology · 2025Review
- Surgical Outcomes of Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in Primary and Secondary Open- and Closed-Angle Glaucoma.Diagnostics (Basel, Switzerland) · 2025Article
- Optimizing the sequential approach of combined phacoemulsification and gonioscopy-assisted transluminal trabeculotomy (GATT) in primary open-angle glaucoma.BMC ophthalmology · 2025Article
- Visual Function After Schlemm's Canal-Based MIGS.Journal of clinical medicine · 2025Review
- Historical and Contemporary Debates in Schlemm's Canal-Based MIGS.Journal of clinical medicine · 2024Review
- Two-Year Retrospective Study of Cataract Surgery and Schlemm Canal Hydrus Microstent in Black and Afro-Latino Patients.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIntraocular pressure (IOP) spikes (IOP > 30 mmHg or > 10 mmHg above baseline IOP) are a common and worrisome complication of gonioscopy-assisted transluminal trabeculotomy (GATT). The purpose of this study is to identify risk factors for IOP spikes and to describe their characteristics, management, and clinical course in a large cohort of patients.
methodsA retrospective, single-center study which included 217 consecutive eyes of patients that underwent GATT between December 2019 and April 2022 with follow-up of at least 90 days.
resultsIOP spikes occurred in 52 of 217 (24%) eyes. Spikes occurred in 15.5% of patients in whom pre-operative IOP-lowering medications were continued after surgery (90 eyes), and in 29.9% in whom IOP-lowering medications were stopped after surgery (127 eyes). Spikes were diagnosed at a mean of 7.7 ± 6.5 days after surgery. All IOP spikes occurred within the first month of surgery. The mean duration of a spike was 4.9 ± 5.4 days. Management of IOP spikes included adding a mean of 3.13 ± 1.7 groups of glaucoma medications. Thirty-seven (72.5%) eyes were treated with oral carbonic anhydrase inhibitor, 11 (21.6%) were treated with IV mannitol, and anterior chamber paracentesis was performed in 16 (31.4%). Six (11.8%) eyes underwent additional glaucoma surgery to control IOP. Patients that continued their pre-operative IOP-lowering medications after surgery were 2.3 times less likely to develop a spike as compared to patients who discontinued their medications (P = 0.016). Spikes were found to be a risk factor for failure of GATT.
conclusionsIOP spikes are a common occurrence after GATT. They most commonly appear during the first two post-operative weeks and usually resolve with topical and systemic IOP-lowering treatment. The continuation of IOP-lowering medications after GATT is recommended to lower the risk of IOP spikes.
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