Evidence map›Paper›PMID 37843306›Full record

ArticleInfection and immunity2023

Bhlhe40 limits early IL-10 production from CD4

Kara A O'Neal, Sheldon L Zeltner, Camille L Foscue, Jason S Stumhofer

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kara A O'NealDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences , Little Rock, Arkansas, USA.
Sheldon L ZeltnerDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences , Little Rock, Arkansas, USA.
Camille L FoscueDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences , Little Rock, Arkansas, USA.
Jason S StumhoferDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences , Little Rock, Arkansas, USA.ORCID 0000-0003-2583-0206
University of Arkansas for Medical Sciences · US

Funding

Arkansas Center for Clinical and Translational ResearchUL1TR000039 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI BECK, CORNELIA MARIE, JAMES, LAURA P · 2012 to 2014
$10.0M
Pilot Grant ProgramP30GM145393 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI MARK S SMELTZER · 2022 to 2026
$7.6M
Regulation and function of B cells during malaria infection- ResubmissionR01AI116653 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI STUMHOFER, JASON S · 2016 to 2020
$2.4M
NCATS NIH HHS UL1 TR000039NIAID NIH HHS R01 AI116653NIGMS NIH HHS P30 GM145393
6 · The paper itself

Abstract

The cytokine IL-10 suppresses T-cell-mediated immunity, which is required to control infection with

Indexed as

Interleukin-10Plasmodium yoeliiAnimalsBasic Helix-Loop-Helix ProteinsCytokinesHomeodomain ProteinsInterferon-gammaMiceMice, Inbred C57BLT-Lymphocytes, RegulatoryBasic Helix-Loop-Helix ProteinsBhlhe40 protein, mouseCytokinesHomeodomain ProteinsInterferon-gammaInterleukin-10cytokinesinfectious diseasePlasmodiumT cellstranscription factors

Identifiers

PMID37843306
PMCPMC10652903
OpenAlexW4387661822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.