ArticleEuropean journal of neurology2024
Pregnancy outcomes for women with myasthenia gravis and their newborns: A nationwide register-based cohort study.
Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Diabetes mellitus in patients with myasthenia gravis: a systematic review and meta-analysis.Endocrine · 2025Pooled it
- Myasthenia Gravis and Pregnancy: Clinical Management and Maternal-Neonatal Outcomes.Medicina (Kaunas, Lithuania) · 2026Review
- Characterizing Perinatal Treatment Patterns and Outcomes in Myasthenia Gravis.Muscle & nerve · 2026Article
- Pregnancy in myasthenia gravis: a retrospective analysis of maternal and neonatal outcome from a large tertiary care centre in Germany.Archives of gynecology and obstetrics · 2024Article
- [Myasthenia gravis-Gender aspects and family planning].Der Nervenarzt · 2024Review
- More evidence is needed for the association between serum myasthenia gravis and adverse pregnancy, delivery, and neonatal outcomes.European journal of neurology · 2024Article
- Response to "More evidence is needed for the association between serum myasthenia gravis and adverse pregnancy, delivery and neonatal outcomes".European journal of neurology · 2024Article
- Transient Neonatal Myasthenia Gravis as a Common Complication of a Rare Disease: A Systematic Review.Journal of clinical medicine · 2024Review
- Pregnancy outcomes for women with myasthenia gravis and their newborns: A nationwide register-based cohort study.European journal of neurology · 2024Article
- The burden of myasthenia gravis - highlighting the impact on family planning and the role of social support.Frontiers in neurology · 2023Article
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6 authors at 3 institutions in 1 country.
Funding
Abstract
background and purposeFew large-scale studies examine whether maternal myasthenia gravis (MG) is a risk factor for complications during pregnancy and childbirth. This study evaluated whether maternal MG is associated with an increased risk of adverse pregnancy, delivery, and neonatal outcomes.
methodsWe conducted a nationwide Swedish register-based cohort study of women who gave birth to singleton infants (≥22 gestational weeks) during 1987-2019. Exposed women were diagnosed with MG before or during the index pregnancy (N = 443). Unexposed women comprised 4249 women without a diagnosis of MG, matched for age, parity, hospital, and year of childbirth. The risks of adverse pregnancy, delivery, and neonatal outcomes for women with MG were estimated using regression modeling and presented as adjusted odds ratios (aOR).
resultsThere was no increased risk of pregnancy complications in women with MG. Women with MG had a spontaneous onset of labor less often than women without MG (69.8% vs. 79.5%; aOR 0.59; p < 0.001) as well as higher labor induction rates and elective cesarean section deliveries (16.0% vs. 12.3%, aOR 1.42; p = 0.02 and 12.0% vs. 8.1%, aOR 1.59; p = 0.009). Infants of women with MG were born on average 2 days earlier (p = 0.002); however, these infants did not have a higher risk of having low APGAR, being small for gestational age, or having a congenital malformation.
conclusionThis first nationwide study of pregnancy in women with MG in Sweden demonstrates reassuring results overall, suggesting generally safe pregnancy outcomes for women with MG and their infants.
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