Evidence map›Paper›PMID 37842468›Full record

ArticleCureus2023

A Rare Case of Myxedema Coma Precipitated by a Single Dose of Haloperidol in a Patient With Paranoid Schizophrenia.

Manuel Menendez, Temilola Majekodunmi, Farah Chohan, Aaron Perez-Castaneda, Hiram Maldonado Rivera, Eugenio Angueira-Serrano, George Michel

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Manuel MenendezInternal Medicine, Ross University School of Medicine, Bridgetown, BRB.
Temilola MajekodunmiInternal Medicine, Larkin Community Hospital, South Miami, USA.
Farah ChohanInternal Medicine, Larkin Community Hospital, South Miami, USA.
Aaron Perez-CastanedaInternal Medicine, Larkin Community Hospital, South Miami, USA.
Hiram Maldonado RiveraEndocrinology, Larkin Community Hospital, South Miami, USA.
Eugenio Angueira-SerranoEndocrinology, Larkin Community Hospital Palm Springs Campus, Hialeah, USA.
George MichelInternal Medicine, Larkin Community Hospital, South Miami, USA.
Ross University School of Medicine · BBLarkin Community Hospital · USPalm Springs General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myxedema coma is a rare and potentially life-threatening condition that occurs when severe hypothyroidism is untreated or inadequately managed. It is characterized by a rapid drop in mental status, hypothermia, respiratory failure, hypotension, and other symptoms of severe metabolic dysfunction. The condition primarily affects older women with a history of thyroid dysfunction but can occur in any age or gender group. A common trigger for this condition is seen with a drop in atmospheric temperatures or during the cold winter months. However, a rare, poorly documented trigger is recent antipsychotic use in severe hypothyroid states. The diagnosis of myxedema coma requires prompt recognition and treatment, as delays can result in significant morbidity and mortality which is the objective of this case report.

Indexed as

antipsychotic useendocrine disorderhaldolhypothalamic-pituitary axishypothyroid myxedema comasevere hypothyroid statesthyroid dysfunctionthyroid replacement therapy

Identifiers

PMID37842468
PMCPMC10571067
OpenAlexW4386752369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.