Evidence map›Paper›PMID 37842198›Full record

ArticleGastroenterology report2023

Predicted pro-inflammatory hs-CRP score and non-alcoholic fatty liver disease.

Akinkunmi Paul Okekunle, Jiyoung Youn, Sihan Song, Goh Eun Chung, Sun Young Yang, Young Sun Kim, Jung Eun Lee

Open access · diamondAbstract read
In one paragraph

Article in Gastroenterology report, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

  1. Liver fibrosis risk: a silent threat in type 1 diabetes mellitus.Journal of endocrinological investigation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Akinkunmi Paul OkekunleDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0003-4825-4934
Jiyoung YounDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.
Sihan SongDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.
Goh Eun ChungHealthcare System Gangnam Center, Healthcare Research Institute, Seoul National University Hospital, Seoul, Korea.
Sun Young YangHealthcare System Gangnam Center, Healthcare Research Institute, Seoul National University Hospital, Seoul, Korea.
Young Sun KimHealthcare System Gangnam Center, Healthcare Research Institute, Seoul National University Hospital, Seoul, Korea.
Jung Eun LeeDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0003-1141-878X
Seoul National University · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is a major contributor to liver diseases globally, yet there are limited studies investigating the impact of diet and lifestyle factors on its development. This study aimed to examine the association between the prevalence of NAFLD and predicted pro-inflammatory high-sensitivity C-reactive protein (hs-CRP) score. Methods: We included 1,076 Korean adults who underwent a medical examination at the Seoul National University Hospital Gangnam Healthcare Center in Korea between May and December 2011 and updated in 2021. The predicted pro-inflammatory hs-CRP score was derived from pro-inflammatory demographic, lifestyle, dietary, and anthropometric factors, and NAFLD was diagnosed using liver ultrasound. Multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) of NAFLD odds according to predicted pro-inflammatory hs-CRP score were estimated using logistic regression at a two-sided Results: Among the 1,076 participants, 320 had NAFLD. The multivariable-adjusted ORs and 95% CIs for NAFLD by tertiles of predicted pro-inflammatory hs-CRP score were 1.00, 3.30 (2.06, 5.30), 18.25 (10.47, 31.81; Conclusions: Predicted pro-inflammatory hs-CRP score was associated with higher odds of NAFLD. Adopting dietary and lifestyle changes related to lower inflammation might be a valuable strategy for preventing NAFLD.

Indexed as

fatty liverhigh-sensitivity C-reactive proteinnon-alcoholic fatty liver diseasepro-inflammation

Identifiers

PMID37842198
PMCPMC10568523
OpenAlexW4387588579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.