Evidence map›Paper›PMID 37841918›Full record

ArticleFrontiers in pharmacology2023

A pilot study of cerebral metabolism and serotonin 5-HT

Klemens Egger, Frederik Gudmundsen, Naja Støckel Jessen, Christina Baun, Sandra N Poetzsch, Vladimir Shalgunov, Matthias M Herth, Boris B Quednow, Chantal Martin-Soelch, Dario Dornbierer and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06252506 (Molecular Imaging Study of Harmine/DMT), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06252506 phase1completednot on this mapstarted 2024, after this paper: background citation

Molecular Imaging Study of Harmine/DMT: a Basic Research Approach

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2024 to 2025Enrolled17ConditionsNeuropharmacological Investigation of Ayahuasca Constituents DMT and HarmineArmsN,N-dimethyltryptamine (DMT) + harmine, Placebo
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Registered Clinical Trials of Ayahuasca and DMT: A Scoping Review.Clinical pharmacology and therapeutics · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Klemens EggerDepartment of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Frederik GudmundsenDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.
Naja Støckel JessenDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.
Christina BaunDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.
Sandra N PoetzschDepartment of Forensic Pharmacology and Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland.
Vladimir ShalgunovDepartment of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Matthias M HerthDepartment of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Boris B QuednowDepartment of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Chantal Martin-SoelchDepartment of Psychology, University Fribourg, Fribourg, Switzerland.
Dario DornbiererDepartment of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Milan ScheideggerDepartment of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Paul Cumming *Department of Nuclear Medicine, Bern University Hospital, Bern, Switzerland.
Mikael Palner *Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
University of Zurich · CHUniversity of Copenhagen · DKUniversity of Southern Denmark · DKQueensland University of Technology · AUUniversity of Fribourg · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

[18 F]FDG-PETayahuascaDMTharminepharmahuascaPKPDpsychedelicsserotonin receptor

Identifiers

PMID37841918
PMCPMC10568461
OpenAlexW4387305009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.