Evidence map›Paper›PMID 37841386›Full record

ArticlePHAGE (New Rochelle, N.Y.)2023

Novel

Janet Yakubu Nale, Benjamin Chan, Nnaemeka Emmanuel Nnadi, Jeffrey Kwok Jone Cheng, Susan Matts, Neda Nezam-Abadi, Christopher Jason Richard Turkington, Lucie Manon Charreton, Harroop Bola, Ramez Nazir and 28 more

Abstract read
In one paragraph

Article in PHAGE (New Rochelle, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Potential Roles of Prophages in the Pathogenicity ofAntibiotics (Basel, Switzerland) · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Janet Yakubu NaleDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Benjamin ChanDepartment of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA.
Nnaemeka Emmanuel NnadiDepartment of Microbiology, Faculty of Natural and Applied Sciences, Plateau State University, Bokkos, Nigeria.ORCID https://orcid.org/0000-0002-8424-4859
Jeffrey Kwok Jone ChengDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Susan MattsDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Neda Nezam-AbadiDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Christopher Jason Richard TurkingtonDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Lucie Manon CharretonDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Harroop BolaDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Ramez NazirDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Abubakar Shaaban HozaDepartment of Veterinary Microbiology, Parasitology & Biotechnology, College of Veterinary Medicine & Biomedical Sciences, Sokoine University of Agriculture, Morogoro, Tanzania.
Samuel Posian WamalaDepartment of Biotechnical and Diagnostic Science, College of Veterinary Medicine, Makerere University, Kampala, Uganda.
Ivan IbandaDepartment of Pharmacology and Therapeutics, School of Medicine and Surgery, King Ceasor University, Kampala, Uganda.
Alice Nyambura MainaDepartment of Biology, University of Nairobi, Nairobi, Kenya.
Auleria Ajiambo ApopoFish Quality Control Laboratory, Kenya Fisheries Service, Nairobi, Kenya.
Venance Theophil MsoffeDepartment of Biological Sciences, Mkwawa University College of Education, The Constituent College of University of Dar es Salaam, Iringa, Tanzania.
Nyambura MoremiDepartment of Research, National Public Health Laboratory, Dar es Salaam, Tanzania.
Grace Wanjiru MooreCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Ismail AsiimweDepartment of Biomolecular Resources and Biolab Sciences, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Alice NamatovuDepartment of Biomolecular Resources and Biolab Sciences, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Paul MutumbaDepartment of Biomolecular Resources and Biolab Sciences, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Deus KamyaDepartment of Biomolecular Resources and Biolab Sciences, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Ritah NabunjeDepartment of Biomolecular Resources and Biolab Sciences, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Immaculate NakabugoDepartment of Biomolecular Resources and Biolab Sciences, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Rudovick Ruben KazwalaDepartment of Veterinary Medicine & Public Health, College of Veterinary Medicine & Biomedical Sciences, Sokoine University of Agriculture, Morogoro, Tanzania.
Erastus KangetheDepartment of Public Health, Pharmacology and Toxicology, University of Nairobi, Nairobi, Kenya.
Abel Abera NegashArmauer Hansen Research Institute, Addis Ababa, Ethiopia.
Arthur Kalyebi WateloDepartment of Immunology, Uganda Virus Research Institute, Uganda.
Nelson BukambaMountain Gorilla Veterinary Project Inc, Department of Wildlife and Aquatic Resources Management, College of Veterinary Medicine, Makerere University Kampala, Uganda.
Gideon MuhindoBiogas Solutions Limited, Kampala, Uganda.
Nathan Musisi LubowaDepartment of Biotechnical and Diagnostic Science, College of Veterinary Medicine, Makerere University, Kampala, Uganda.
Ngalla JillaniPhage Biology Laboratory, Institute of Primate Research, Karen Nairobi, Kenya.
Atunga NyachieoPhage Biology Laboratory, Institute of Primate Research, Karen Nairobi, Kenya.
George NasinyamaDepartment of Public Health Kampala International University, Kampala, Uganda.
Jesca NakavumaDepartment of Biomolecular Resources and Biolab Sciences, School of Biosecurity, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Andrew MillardDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.ORCID https://orcid.org/0000-0002-3895-2854
Tobi Elaine NagelPhages for Global Health, Oakland, California, USA.
Martha Rebecca Jane ClokieDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The antimicrobial resistance catastrophe is a growing global health threat and predicted to be worse in developing countries. Phages for Global Health (PGH) is training scientists in these regions to isolate relevant therapeutic phages for pathogenic bacteria within their locality, and thus contributing to making phage technology universally available. Materials and Methods: During the inaugural PGH workshop in East Africa, samples from Ugandan municipal sewage facilities were collected and two novel Results: The phages, UP19 (capsid diameter ∼100 nm, contractile tail ∼120/20 nm) and UP30 (capsid diameter ∼70 nm, noncontractile tail of ∼170/20 nm), lysed ∼82% and ∼36% of the 11 clinical isolates examined, respectively. The genomes of UP19 (171.402 kb, 282 CDS) and UP30 (49.834 kb, 75 CDS) closely match the genera Conclusion: The phages isolated have therapeutic potential for further development against

Indexed as

antimicrobial resistanceEscherichia coli phagePhages for Global Healthphage therapy

Identifiers

PMID37841386
PMCPMC10574529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.