Evidence map›Paper›PMID 37841258›Full record

ArticleFrontiers in immunology2023

A novel [

Ander Puyalto, María Rodríguez-Remírez, Inés López, Fabiola Iribarren, Jon Ander Simón, Marga Ecay, María Collantes, Anna Vilalta-Lacarra, Alejandro Francisco-Cruz, Jose Luis Solórzano and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Imaging Immunotherapy.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Ander PuyaltoDepartment of Medical Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
María Rodríguez-RemírezDepartment of Medical Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
Inés LópezUniversity of Navarra, Cima-University of Navarra, Program in Solid Tumors, Pamplona, Spain.
Fabiola IribarrenDepartment of Medical Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
Jon Ander SimónUniversity of Navarra, Cima-University of Navarra, Program in Solid Tumors, Pamplona, Spain.
Marga EcayDepartment of Nuclear Medicine, Clínica Universidad de Navarra, Pamplona, Spain.
María CollantesDepartment of Nuclear Medicine, Clínica Universidad de Navarra, Pamplona, Spain.
Anna Vilalta-LacarraDepartment of Medical Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
Alejandro Francisco-CruzDepartment of Pathology, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico.
Jose Luis SolórzanoDepartamento de Anatomía Patológica y Diagnóstico Molecular, Md Anderson Cancer Center, Madrid, Spain.
Sergio SandiegoDepartment of Oncology, Fundación Instituto Valenciano de Oncología (FIVO), Valencia, Spain.
Iván PeñuelasInstituto de Investigación Sanitaria de Navarra (IDISNA), Pamplona, Spain.
Alfonso CalvoUniversity of Navarra, Cima-University of Navarra, Program in Solid Tumors, Pamplona, Spain.
Daniel AjonaUniversity of Navarra, Cima-University of Navarra, Program in Solid Tumors, Pamplona, Spain.
Ignacio Gil-BazoDepartment of Medical Oncology, Clínica Universidad de Navarra, Pamplona, Spain.
Clinica Universidad de Navarra · ESUniversidad de Navarra · ESNavarre Institute of Health Research · ESCentro de Investigación Biomédica en Red de Cáncer · ESFundación Instituto Valenciano de Oncología · ESInstituto Nacional de Cardiología · MXMD Anderson Cancer Center Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Harnessing the anti-tumor immune system response by targeting the program cell death protein (PD-1) and program cell death ligand protein (PD-L1) axis has been a major breakthrough in non-small cell lung cancer (NSCLC) therapy. Nonetheless, conventional imaging tools cannot accurately assess response in immunotherapy-treated patients. Using a lung cancer syngeneic mouse model responder to immunotherapy, we aimed to demonstrate that [ Materials and methods: A syngeneic mouse model responder to anti-PD-1 therapy was used. Tumor growth and response to PD-1 blockade were monitored by conventional 2-deoxy-2-[ Results: Conventional [ Conclusion: Our data may support the clinical implementation of immuno-PET as a promising novel imaging tool to predict and assess the response of PD-1/PD-L1 inhibitors in patients with NSCLC.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsAnimalsB7-H1 AntigenFluorodeoxyglucose F18HumansImmune Checkpoint InhibitorsMicePositron Emission Tomography Computed TomographyProgrammed Cell Death 1 ReceptorB7-H1 AntigenFluorodeoxyglucose F18Immune Checkpoint InhibitorsProgrammed Cell Death 1 Receptorimmuno-PETinhibitor of differentiation 1lung adenocarcinomaPD-1 inhibitionpseudoprogression

Identifiers

PMID37841258
PMCPMC10569300
OpenAlexW4387183515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.