Evidence map›Paper›PMID 37841134›Full record

ArticleACS omega2023

Preliminary Findings on the Salivary Metabolome of Hookah and Cigarette Smokers.

Ellen Greenfield, Mariana de Sá Alves, Fernanda Rodrigues, Júlia Oliveira Nogueira, Letícia Ferrari da Silva, Henrique Pereira de Jesus, Desiree Rosa Cavalcanti, Bruna Fernandes do Carmo Carvalho, Janete Dias Almeida, Maria Anita Mendes and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Salivary Metabolic Pathway Alterations in Brazilian E-Cigarette Users.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ellen GreenfieldTechnology Research Center (NPT), Universidade de Mogi das Cruzes, Mogi das Cruzes 08780-911, Brazil.
Mariana de Sá AlvesDepartment of Biosciences and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos, São Paulo 01049-010, Brazil.
Fernanda RodriguesTechnology Research Center (NPT), Universidade de Mogi das Cruzes, Mogi das Cruzes 08780-911, Brazil.
Júlia Oliveira NogueiraSchool of Dentistry, Universidade Mogi das Cruzes, Mogi das Cruzes 08780-911, Brazil.
Letícia Ferrari da SilvaSchool of Dentistry, Universidade Mogi das Cruzes, Mogi das Cruzes 08780-911, Brazil.
Henrique Pereira de JesusSchool of Dentistry, Universidade Mogi das Cruzes, Mogi das Cruzes 08780-911, Brazil.
Desiree Rosa CavalcantiSchool of Dentistry, Universidade Mogi das Cruzes, Mogi das Cruzes 08780-911, Brazil.
Bruna Fernandes do Carmo CarvalhoDepartment of Biosciences and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos, São Paulo 01049-010, Brazil.
Janete Dias AlmeidaDepartment of Biosciences and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos, São Paulo 01049-010, Brazil.
Maria Anita MendesDempster MS Lab, Department of Chemical Engineering, Polytechnic School, University of Sao Paulo, Sao Paulo 05508-900, Brazil.
Mônica Ghislaine Oliveira AlvesTechnology Research Center (NPT), Universidade de Mogi das Cruzes, Mogi das Cruzes 08780-911, Brazil.ORCID https://orcid.org/0000-0002-3411-9443
Universidade Estadual Paulista (Unesp) · BRUniversidade de Mogi das Cruzes · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to evaluate the salivary metabolomic profile of patients who habitually smoke hookah and cigarettes. The groups consisted of 33 regular and exclusive hookah smokers, 26 regular and exclusive cigarette smokers, and 30 nonsmokers. Unstimulated whole saliva was collected for the measurement of salivary metabolites by gas chromatography coupled with tandem mass spectrometry (GC-MS/MS). The MetaboAnalyst software was used for statistical analysis and evaluation of biomarkers. 11 smoking salivary biomarkers were identified using the area under receiving-operator curver criterion and threshold of 0.9. Xylitol and octadecanol were higher in cigarette smokers compared to controls; arabitol and maltose were higher in controls compared to cigarette smokers; octadecanol and tyramine were higher in hookah smokers compared to controls; phenylalanine was higher in controls compared to hookah smokers; and fructose, isocitric acid, glucuronic acid, tryptamine, maltose, tyramine, and 3-hydroxyisolvaleric acid were higher in hookah smokers compared to cigarettes smokers. Conclusions: The evaluation of the salivary metabolome of hookah smokers, showing separation between the groups, especially between the control versus hookah groups and cigarette versus hookah groups, and it seems to demonstrate that the use of hookah tobacco is more damaging to health.

Identifiers

PMID37841134
PMCPMC10569005
OpenAlexW4387215299

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.