Evidence map›Paper›PMID 37841100›Full record

ArticleAccess microbiology2023

Haemophagocytic lymphohistiocytosis after intravesical BCG administration for bladder cancer presenting with multiorgan failure.

G D Liatsos, G Manousopoulou, A Poulaki, A Iliaki, I Mariolis, D Vassilopoulos

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Access microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review of BCG immunotherapy for bladder cancer.Clinical microbiology reviews · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

G D LiatsosDepartment of Internal Medicine, "Hippokration" General Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-8203-2748
G Manousopoulou2nd Department of Medicine and Laboratory, School of Medicine, National and Kapodistrian University of Athens, "Hippokration" General Hospital, Athens, Greece.
A Poulaki2nd Department of Medicine and Laboratory, School of Medicine, National and Kapodistrian University of Athens, "Hippokration" General Hospital, Athens, Greece.
A Iliaki2nd Department of Medicine and Laboratory, School of Medicine, National and Kapodistrian University of Athens, "Hippokration" General Hospital, Athens, Greece.
I Mariolis2nd Department of Medicine and Laboratory, School of Medicine, National and Kapodistrian University of Athens, "Hippokration" General Hospital, Athens, Greece.
D Vassilopoulos2nd Department of Medicine and Laboratory, School of Medicine, National and Kapodistrian University of Athens, "Hippokration" General Hospital, Athens, Greece.
National and Kapodistrian University of Athens · GRHippocration General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacillus Calmette-Guérin (BCG), is administered intravesically as an adjuvant immunotherapy for the treatment of non-muscle invasive bladder cancer. While mild non-infectious problems can occur in up to 85 % of cases, significant local and systemic complications have been reported in 1-5 % of cases. We report the case of a patient with superficial bladder cancer who developed multiorgan failure after intravesical BCG instillation including the kidney and liver with subsequent haemophagocytic lymphohistiocytosis. Our case illustrates the first reported combination of secondary haemophagocytic lymphohistiocytosis with severe renal and liver failure after BCG immunotherapy for bladder carcinoma. Treatment strategy is discussed.

Indexed as

BCGhaemophagocytosisintravesicalkidney injuryliver failure

Identifiers

PMID37841100
PMCPMC10569663
OpenAlexW4387166389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.