Evidence map›Paper›PMID 37841053›Full record

ReviewFrontiers in allergy2023

Factors and co-factors influencing clinical manifestations in nsLTPs allergy: between the good and the bad.

Erminia Ridolo, Alessandro Barone, Martina Ottoni, Silvia Peveri, Marcello Montagni, Francesca Nicoletta

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in allergy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. IgE-mediated lipid transfer protein allergy in children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  5. Immunoglobulin E (IgE)-mediated food allergy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Review
  6. The Diagnosis of Allergy to Lipid Transfer Proteins.Current allergy and asthma reports · 2024
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Erminia RidoloDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Alessandro BaroneAllergology Unit, University Hospital of Parma, Parma, Italy.
Martina OttoniAllergology Unit, University Hospital of Parma, Parma, Italy.
Silvia PeveriDepartmental Unit of Allergology, Guglielmo da Saliceto Hospital, Piacenza, Italy.
Marcello MontagniDepartmental Unit of Allergology, Guglielmo da Saliceto Hospital, Piacenza, Italy.
Francesca NicolettaAllergology Unit, University Hospital of Parma, Parma, Italy.
University of Parma · ITGuglielmo da Saliceto Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-specific lipid transfer proteins (nsLTPs) are a family of plant pan-allergens that represent the primary cause of food allergies in the Mediterranean area, characterized by a wide range of clinical manifestations, ranging from the total absence of symptoms up to anaphylaxis. This wide variety of symptoms is related to the intrinsic capacity of nsLTPs to cause an allergic reaction in a specific subject, but also to the presence of co-factors exacerbating (i.e., exercise, NSAIDs, PPIs, alcohol, cannabis, prolonged fasting, menstruation, acute infections, sleep deprivation, chronic urticaria) or protecting from (i.e., co-sensitization to PR10, profilin or polcalcin) severe reactions. In this picture, recognizing some nsLTPs-related peculiarities (i.e., route, type and number of sensitizations, concentration of the allergen, cross-reactions) and eventual co-factors may help the allergist to define the risk profile of the single patient, in order to promote the appropriate management of the allergy from dietary advices up to the prescription of life-saving epinephrine autoinjector.

Indexed as

anaphylaxisco-factorcross-reactionfood allergyfood sensitizationlipid transfer protein

Identifiers

PMID37841053
PMCPMC10568476
OpenAlexW4387305013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.