ArticleFrontiers in neurology2023
The thalamus and basal ganglia are smaller in children with epilepsy after perinatal stroke.
Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Assessing cognitive impairment in epilepsy using Arterial spin-labeled (ASL) perfusion imaging.Brain imaging and behavior · 2026Article
- Abnormalities of thalamus and thalamocortical pathways in patients with refractory epilepsy caused by focal cortical dysplasia - MRI study.Epilepsia open · 2025Article
- Review
- Brain growth until adolescence after a neonatal focal injury: sex related differences beyond lesion effect.Frontiers in neuroscience · 2024Article
- General ability and specific cognitive functions are lower in children with epilepsy after perinatal ischemic stroke.Frontiers in stroke · 2024Article
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8 authors.
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Abstract
Background: Epilepsy is one of the most serious consequences of perinatal stroke. Epilepsy itself has been proposed as a risk factor for impaired cognitive, language, and behavioral functioning. It is still unclear which children develop epilepsy after perinatal stroke. The current study aimed to evaluate the volume of the thalamus and the basal ganglia in children after perinatal stroke in relation to poststroke epilepsy. Methods: The follow-up study included 29 children with perinatal arterial ischemic stroke (AIS), 33 children with presumed periventricular venous infarction (PVI), and 46 age- and sex-matched healthy controls. Magnetic resonance imaging was performed in children between the ages of 4 and 18 years, and volumetric analysis by segmentation was used to evaluate the size of the thalamus, caudate nucleus, putamen, globus pallidus, hippocampus, amygdala, and nucleus accumbens. Results: During a median follow-up time of 12.8 years [interquartile range (IQR): 10.8-17.3] in the AIS group and 12.5 years (IQR: 9.3-14.8) in the PVI group ( Conclusion: In children with AIS, epilepsy or IED occurred more often compared to children with PVI. Both patients with AIS and PVI with severe damage to the basal ganglia and the thalamus have a higher risk of developing poststroke epilepsy and should be monitored more closely throughout childhood to initiate timely antiseizure medication and rehabilitation.
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