Evidence map›Paper›PMID 37840587›Full record

ArticleEuropean heart journal open2023

Intima-media thickness at the near or far wall of the common carotid artery in cardiovascular risk assessment.

Lisa Seekircher, Lena Tschiderer, Lars Lind, Maya S Safarova, Maryam Kavousi, M Arfan Ikram, Eva Lonn, Salim Yusuf, Diederick E Grobbee, John J P Kastelein and 29 more

Open access · goldAbstract read
In one paragraph

Article in European heart journal open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors at 20 institutions in 14 countries.

Lisa SeekircherInstitute of Health Economics, Department of Medical Statistics, Informatics, and Health Economics, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.ORCID https://orcid.org/0000-0003-0260-3262
Lena TschidererInstitute of Health Economics, Department of Medical Statistics, Informatics, and Health Economics, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.ORCID https://orcid.org/0000-0001-7988-853X
Lars LindDepartment of Medicine, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0003-2335-8542
Maya S SafarovaDivision of Cardiovascular Medicine, Department of Medicine, Froedtert and Medical College of Wisconsin, Milwaukee, WI, USA.
Maryam KavousiDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-5976-6519
M Arfan IkramDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-0372-8585
Eva LonnDepartment of Medicine and Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Salim YusufDepartment of Medicine and Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Diederick E GrobbeeJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
John J P KasteleinDepartment of Vascular Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Frank L J VisserenDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Matthew WaltersSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK.
Jesse DawsonInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Peter HigginsInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Stefan AgewallDepartment of Clinical Sciences, Division of Cardiology, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
Alberico CatapanoDepartment of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Eric de GrootImagelabonline & Cardiovascular, Erichem, The Netherlands.
Mark A EspelandDepartment of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Gerhard KlingenschmidDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Dianna MaglianoDepartment of Epidemiology and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Australia.
Michael H OlsenDepartment of Internal Medicine, Holbaek Hospital, University of Southern Denmark, Odense, Denmark.
David PreissNuffield Department of Population Health, MRC Population Health Research Unit, Clinical Trial Service Unit, University of Oxford, Oxford, UK.
Dirk SanderDepartment of Neurology, Benedictus Hospital Tutzing & Feldafing, Feldafing, Germany.
Michael SkiltonFaculty of Medicine and Health, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia.
Dorota A Zozulińska-ZiółkiewiczDepartment of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Muriel P C GrootemanDepartment of Nephrology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, Amsterdam, The Netherlands.
Peter J BlankestijnDepartment of Nephrology, University Medical Center Utrecht, Utrecht, The Netherlands.
Kazuo KitagawaDepartment of Neurology, Tokyo Women's Medical University, Tokyo, Japan.
Shuhei OkazakiDepartment of Neurology, Osaka University Graduate School of Medicine, Osaka, Japan.
Maria V ManziDepartment of Advanced Biomedical Sciences, Federico II University, Naples, Italy.
Costantino MancusiDepartment of Advanced Biomedical Sciences, Federico II University, Naples, Italy.ORCID https://orcid.org/0000-0001-6690-1408
Raffaele IzzoDepartment of Advanced Biomedical Sciences, Federico II University, Naples, Italy.ORCID https://orcid.org/0000-0002-0308-2836
Moise DesvarieuxDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Tatjana RundekDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
Hertzel C GersteinDepartment of Medicine and Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Michiel L BotsJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Michael J SweetingDepartment of Health Sciences, University of Leicester, Leicester, UK.
Matthias W LorenzDepartment of Neurology, Goethe University, Frankfurt am Main, Germany.
Peter WilleitInstitute of Health Economics, Department of Medical Statistics, Informatics, and Health Economics, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.ORCID https://orcid.org/0000-0002-1866-7159
Innsbruck Medical University · ATUniversity Medical Center Utrecht · NLFederico II University Hospital · ITHamilton General Hospital · CAUniversity of Glasgow · GBErasmus MC · NLAmsterdam Neuroscience · NLAmsterdam UMC Location University of Amsterdam · NLFroedtert Hospital · USGoethe University Frankfurt · DEInserm · FRMonash University · AUPoznan University of Medical Sciences · PLTechnical University of Munich · DEThe University of Osaka · JPThe University of Sydney · AUTokyo Women's Medical University · JPUniversity of Amsterdam · NLUniversity of Leicester · GBUniversity of Miami · US

Funding

NOVEL FACTORS FOR UNEXPLAINED PHENOTYPES OF SUBCLINICAL CAROTID ATHEROSCLEROSISR01NS065114 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BLANTON, SUSAN HALLORAN, RUNDEK, TATJANA · 2010 to 2014
$1.7M
NINDS NIH HHS R01 NS065114
6 · The paper itself

Abstract

Aims: Current guidelines recommend measuring carotid intima-media thickness (IMT) at the far wall of the common carotid artery (CCA). We aimed to precisely quantify associations of near vs. far wall CCA-IMT with the risk for atherosclerotic cardiovascular disease (CVD, defined as coronary heart disease or stroke) and their added predictive values. Methods and results: We analysed individual records of 41 941 participants from 16 prospective studies in the Proof-ATHERO consortium {mean age 61 years [standard deviation (SD) = 11]; 53% female; 16% prior CVD}. Mean baseline values of near and far wall CCA-IMT were 0.83 (SD = 0.28) and 0.82 (SD = 0.27) mm, differed by a mean of 0.02 mm (95% limits of agreement: -0.40 to 0.43), and were moderately correlated [ Conclusions: The associations of near and far wall CCA-IMT with incident CVD were positive, approximately linear, and similarly strong. Improvement in risk discrimination was highest when CCA-IMT was measured at both walls.

Indexed as

Cardiovascular riskCommon carotid artery intima-media thicknessIndividual-participant-data meta-analysis

Identifiers

PMID37840587
PMCPMC10575622
OpenAlexW4386946768

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.