Evidence map›Paper›PMID 37840568›Full record

ArticleExperimental and therapeutic medicine2023

Abscopal effect with fever of unknown cause during radiotherapy: Two case reports and review of the literature.

Yoshiko Oshiro, Masashi Mizumoto, Takayuki Hisanaga, Ken Tanaka, Manabu Komine, Mizuki Takahashi, Koji Kikuchi, Hideyuki Sakurai

Abstract readCase Reports
In one paragraph

Article in Experimental and therapeutic medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yoshiko OshiroDepartment of Radiation Oncology, Tsukuba Medical Center Hospital, Tsukuba, Ibaraki 305-8558, Japan.
Masashi MizumotoDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Takayuki HisanagaDepartment of Palliative Medicine, Tsukuba Medical Center Hospital, Tsukuba, Ibaraki 305-8558, Japan.
Ken TanakaDepartment of Urology, Tsukuba Medical Center Hospital, Tsukuba, Ibaraki 305-8558, Japan.
Manabu KomineDepartment of Urology, Tsukuba Medical Center Hospital, Tsukuba, Ibaraki 305-8558, Japan.
Mizuki TakahashiDepartment of Radiation Oncology, Tsukuba Medical Center Hospital, Tsukuba, Ibaraki 305-8558, Japan.
Koji KikuchiDepartment of Urology, Tsukuba Medical Center Hospital, Tsukuba, Ibaraki 305-8558, Japan.
Hideyuki SakuraiDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The abscopal effect is a rare phenomenon that is defined as regression of tumor lesions distant from irradiation targets. At our department, two cases with an abscopal effect with fever of unknown cause (FUC) and an inflammatory response during radiotherapy were encountered. Radiotherapy is a local treatment; therefore, it rarely causes systemic side effects during radiotherapy, and if a patient develops a fever during radiotherapy, it is frequently considered tumor fever. We experienced 2 cases of FUC during irradiation followed by abscopal effect. The obvious relationship between the abscopal effect and the fever remains to be clarified. However, FUC during radiotherapy may be a hint to the abscopal effect, considering that immune response and cytokines are closely related to the abscopal effect.

Indexed as

abscopal effectpleomorphic sarcomaradiotherapyrenal cell carcinomaunknown fever

Identifiers

PMID37840568
PMCPMC10570764

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.