Evidence map›Paper›PMID 37840550›Full record

ArticleAutophagy reports2022

Lipid droplets in stress protection: distinct mechanisms of lipid droplet microautophagy.

Pin-Chao Liao, Liza A Pon

Abstract read
In one paragraph

Article in Autophagy reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pin-Chao LiaoDepartment of Pathology and Cell Biology, Columbia University, New York, NY 10032, United States.
Liza A PonDepartment of Pathology and Cell Biology, Columbia University, New York, NY 10032, United States.

Funding

Mitochondrial inheritance and quality controlR35GM122589 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Liza A Pon · 2017 to 2026
$5.1M
The Role of Actin in Cellular AgingR33AG051047 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PON, LIZA A · 2018 to 2020
$1.4M
The Role of Actin in Cellular AgingR21AG051047 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PON, LIZA A · 2016 to 2017
$427k
NIA NIH HHS R21 AG051047NIA NIH HHS R33 AG051047NIGMS NIH HHS R35 GM122589
6 · The paper itself

Abstract

Lipid droplets (LDs) are organelles that function as sites for lipid storage. LDs have also been implicated in the cellular response to proteotoxic or lipotoxic stress as sites for sequestering dysfunctional or excess proteins or lipids, and targeting those cargos for degradation by LD microautophagy (microlipophagy, μLP). Here, we describe two mechanisms for μLP in yeast, which are triggered by different stressors. μLP occurs at raft-like liquid ordered microdomains in the vacuolar membrane in yeast exposed to severe nutrient limitations. In contrast, in yeast exposed to ER stress or less severe nutrient limitations, LD uptake at the vacuole is liquid ordered (L

Identifiers

PMID37840550
PMCPMC10574811

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.