Evidence map›Paper›PMID 37840414›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Distinguishable Colorimetric Biosensor for Diagnosis of Prostate Cancer Bone Metastases.

Ming Li, Caiping Ding, Dong Zhang, Weiwei Chen, Zejun Yan, Zikang Chen, Zhiyong Guo, Longhua Guo, Youju Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Distinguishable Colorimetric Biosensor for Diagnosis of Prostate Cancer Bone Metastases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ming LiDepartment of Urology & Nephrology, The First Affiliated Hospital of Ningbo University, 59 Liuting Street, Ningbo, Zhejiang, 315010, China.
Caiping DingCollege of Material Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Key Laboratory of Organosilicon Material Technology of Zhejiang Province, Department Hangzhou Normal University, Hangzhou, Zhejiang, 311121, China.ORCID 0000-0002-2066-3392
Dong ZhangDepartment of Urology & Nephrology, The First Affiliated Hospital of Ningbo University, 59 Liuting Street, Ningbo, Zhejiang, 315010, China.
Weiwei ChenCollege of Material Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Key Laboratory of Organosilicon Material Technology of Zhejiang Province, Department Hangzhou Normal University, Hangzhou, Zhejiang, 311121, China.
Zejun YanDepartment of Urology & Nephrology, The First Affiliated Hospital of Ningbo University, 59 Liuting Street, Ningbo, Zhejiang, 315010, China.
Zikang ChenCollege of Material Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Key Laboratory of Organosilicon Material Technology of Zhejiang Province, Department Hangzhou Normal University, Hangzhou, Zhejiang, 311121, China.
Zhiyong GuoState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, State Key Laboratory Base of Novel Functional Materials and Preparation Science, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang, 315211, China.
Longhua GuoCollege of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing, Zhejiang, 314001, China.
Youju HuangCollege of Material Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Key Laboratory of Organosilicon Material Technology of Zhejiang Province, Department Hangzhou Normal University, Hangzhou, Zhejiang, 311121, China.ORCID 0000-0001-5815-9784
Hangzhou Normal University · CNNingbo University · CNJiaxing University · CN

Funding

National Natural Science Foundation of China 22005081National Natural Science Foundation of China 42076193National Natural Science Foundation of China 52222316National Natural Science Foundation of China 82273681Natural Science Foundation of Ningbo City 2023J018Natural Science Foundation of Zhejiang Province LY22B050003Natural Science Foundation of Zhejiang Province LZ22B050001Ningbo Top Medical and Health Research Program 2022020203
6 · The paper itself

Abstract

Castration-resistant prostate cancer (PCa) causes severe bone metastasis (BM), which significantly increases mortality in men with PCa. Imaging tests and radiometric scanning require long analysis times, expensive equipment, specialized personnel, and a slow turnaround. New visualization technologies are expected to solve the above problems. Nonetheless, existing visualization techniques barely meet the urgency for precise diagnosis because the human eyes cannot recognize and capture even slight variations in visual information. By using dye differentiated superposition enhancement colorimetric biosensors, an effective method to diagnose prostate cancer bone metastases (PCa-BM) with excellent accuracy for naked-eye quantitative detection of alkaline phosphatase (ALP) is developed. The biomarker ALP specific hydrolytic product ascorbic acid can be detected by rhodamine derivatives (Rd) as gold nanobipyramids (Au NBPs) are deposited and grown. Color-recombining enhancement effects between Rd and Au NBPs significantly improved abundance. The 150 U L

Indexed as

Biosensing TechniquesBone NeoplasmsProstatic NeoplasmsAlkaline PhosphataseColorimetryHumansMaleAlkaline Phosphatasealkaline phosphatasecolor-recombining enhancementgold nanobipyramidsprostate cancer bone metastasisrhodamine derivatives

Identifiers

PMID37840414
PMCPMC10646272
OpenAlexW4387661932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.