ArticleMultiple sclerosis (Houndmills, Basingstoke, England)2023
Diagnostic delay of multiple sclerosis: prevalence, determinants and consequences.
Article in Multiple sclerosis (Houndmills, Basingstoke, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Diagnostic Delay in Multiple Sclerosis in China: A Nationwide Cross-Sectional Study.Advances in therapy · 2026Article
- Methods of estimating prevalence of multiple sclerosis in six European healthcare data sources: a contribution from the ConcePTION project.European journal of epidemiology · 2026Article
- AI-Based Classification of Multiple Sclerosis Using OCT Retinal Layer Thickness Across Two Centers.Biomedicines · 2026Article
- Patient profiles and disease characteristics of the IMSRN cohort: a multicentre study (2021-2025).The Lancet regional health. Southeast Asia · 2026Article
- Disparities in imaging and management of multiple sclerosis: a review.The British journal of radiology · 2026Review
- The Burden of Multiple Sclerosis in Japan from 1990 to 2021 and Predictions to 2050 Based on the Global Burden of Disease Study 2021.Neuroepidemiology · 2026Article
- A Cross-Sectional Study of Delayed Diagnosis Associated with Gender and Racial Identity in Multiple Sclerosis.Journal of racial and ethnic health disparities · 2025Article
- Multiple sclerosis patients' journey delay in diagnosis and treatment: a multicenter study.BMC neurology · 2025Observational
- Article
- Factors associated with delay to diagnosis of multiple sclerosis in Zambia.Multiple sclerosis (Houndmills, Basingstoke, England) · 2025Article
- Not Just in the Mind: A Case of Neurological Decline in a Young Adult With Psychiatric History.Cureus · 2025Article
- Navigating the Limits of Diagnosis: Young Adults' Experiences of Chronic Living.Sociology of health & illness · 2025Article
- Clinical and epidemiological characteristics of multiple sclerosis in the southern region of the Republic of Azerbaijan.Pakistan journal of medical sciences · 2025Article
- Healthcare use is elevated two decades before a first demyelinating event and differs by age and sex.Annals of clinical and translational neurology · 2025Article
- Diagnostic delays of periodontitis and associated factors: a cross-sectional study.Clinical oral investigations · 2024Article
- Sick leave in the prodromal phase of multiple sclerosis and its association with diagnostic delay: A short report.Multiple sclerosis journal - experimental, translational and clinicalArticle
- Diagnostic delay and misdiagnosis of symptoms reported by patients with multiple sclerosis participating in a research registry.Multiple sclerosis journal - experimental, translational and clinicalArticle
- Diagnostic pathways and barriers in multiple sclerosis in Zambia: A qualitative study.Multiple sclerosis journal - experimental, translational and clinicalArticle
Corrections and comments
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Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly diagnosis and treatment of patients with multiple sclerosis (MS) are associated with better outcomes; however, diagnostic delays remain a major problem.
objectiveDescribe the prevalence, determinants and consequences of delayed diagnoses.
methodsThis single-centre ambispective study analysed 146 adult relapsing-remitting MS patients (2016-2021) for frequency and determinants of diagnostic delays and their associations with clinical, cognitive, imaging and biochemical measures.
resultsDiagnostic delays were identified in 77 patients (52.7%), including 42 (28.7%) physician-dependent cases and 35 (24.0%) patient-dependent cases. Diagnosis was delayed in 22 (15.1%) patients because of misdiagnosis by a neurologist. A longer diagnostic delay was associated with trends towards greater Expanded Disability Status Scale (EDSS) scores (
conclusionDiagnostic delays in MS are common, often determined by early misdiagnosis and associated with greater disease burden.
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