SynthesisBritish journal of anaesthesia2023
Impact of ventilation strategies on pulmonary and cardiovascular complications in patients undergoing general anaesthesia for elective surgery: a systematic review and meta-analysis.
Synthesis in British journal of anaesthesia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Individualised positive end-expiratory pressure to minimise driving pressure and postoperative pulmonary complications in minimally invasive thoracic and abdominal surgery a systematic review and meta-analysis.British journal of anaesthesia · 2026Pooled it
- Intra-operative ventilation strategies and their impact on clinical outcomes: a systematic review and network meta-analysis of randomised trials.Anaesthesia · 2025Pooled it
- Pooled it
- Personalized driving pressure-guided positive end-expiratory pressure in patients at risk of postoperative respiratory failure (IMPROVE-2): a multicenter, pragmatic, randomized clinical trial.Intensive care medicine · 2025Trial
- Driving pressure-guided dynamic PEEP titration reduces atelectasis and improves oxygenation in pediatric laparoscopy: a randomized trial on personalized ventilation strategies.BMC anesthesiology · 2025Trial
- Effect of chronic high-altitude exposure on postoperative pulmonary complications: a retrospective cohort study.Annals of medicine · 2026Article
- [WAKWiN minireview: intraoperative ventilation and postoperative pulmonary complications-Current evidence and concepts for lung protection].Die Anaesthesiologie · 2026Review
- Positive end-expiratory pressure optimisation during general anaesthesia in patients with obesity: a narrative review of respiratory and cardiovascular outcomes.British journal of anaesthesia · 2026Review
- Effects of driving pressure-guided lung-protective ventilation strategy on respiratory mechanics, oxygenation, and postoperative pulmonary complications in patients undergoing minimally invasive esophagectomy: a randomized clinical trial.Journal of thoracic disease · 2025Article
- Robotic-assisted surgery in extremely obese patients: a multidisciplinary approach for a patient with a BMI of 101.7 kg/mArchives of gynecology and obstetrics · 2025Article
- Improved Prediction of Fluid Responsiveness in Ventilated Patients With Low Tidal Volume: The Role of Preload Variation.Critical care explorations · 2025Article
- Predictive effect of postoperative recovery in general anesthesia patients using interpretable models based on swarm intelligence machine learning.Frontiers in physiology · 2025Article
- Developing a dichlorosalicylaldehyde-derived fluorescent probe for monitoring glutathione in a cellular pulmonary ventilation model.Frontiers in chemistry · 2025Article
- Review
- Local anaesthesia with conscious sedation in parotid gland tumour resection: a retrospective review.BMC oral health · 2024Article
- Effects of lung protection ventilation strategies on postoperative pulmonary complications after noncardiac surgery: a network meta-analysis of randomized controlled trials.BMC anesthesiology · 2024Article
- Driving pressure: A useful tool for reducing postoperative pulmonary complications.World journal of critical care medicine · 2024Article
- PEEP on postoperative complications: not to fast.Journal of anesthesia · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany RCTs have evaluated the influence of intraoperative tidal volume (tV), PEEP, and driving pressure on the occurrence of postoperative pulmonary complications, cardiovascular complications, and mortality in adult patients. Our meta-analysis aimed to investigate the association between tV, PEEP, and driving pressure and the above-mentioned outcomes.
methodsWe conducted a systematic review and meta-analysis of RCTs from inception to May 19, 2022. The primary outcome was the incidence of postoperative pulmonary complications; the secondary outcomes were intraoperative cardiovascular complications and 30-day mortality. Primary and secondary outcomes were evaluated stratifying patients in the following groups: (1) low tV (LV, tV 6-8 ml kg
resultsWe included 16 RCTs with a total sample size of 4993. The incidence of postoperative pulmonary complications was lower in patients treated with LV than with HV (OR=0.402, CI 0.280-0.577, P<0.001) and lower in DP than in FP group (OR=0.358, CI 0.187-0.684, P=0.002). Postoperative pulmonary complications did not differ between HP and LP groups; the incidence of intraoperative cardiovascular complications was higher in HP group (OR=1.385, CI 1.027-1.867, P=0.002). The 30-day mortality was not influenced by the ventilation strategy.
conclusionsOptimal intraoperative mechanical ventilation is unclear; however, our meta-analysis showed that low tidal volume and driving pressure-guided PEEP strategies were associated with a reduction in postoperative pulmonary complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.