Evidence map›Paper›PMID 37839923›Full record

Observational studyPancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]2023

Incident diabetes following acute pancreatitis in a multicenter prospective observational cohort.

Joseph Bejjani, Georgios I Papachristou, Kathleen Dungan, Anna Evans Phillips, Vikesh Singh, Frederico Gs Toledo, Samuel Han, Somashekar G Krishna, Ali Lahooti, Peter J Lee and 7 more

Registry-linked trialOpen access · greenAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03063398 (PAPPEI), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03063398 completednot on this map

PAPPEI: Post Acute Pancreatitis Pancreatic Exocrine Insufficiency

TypeobservationalSponsorOhio State UniversityRan2017 to 2024Enrolled196ConditionsAcute PancreatitisArmsNo intervention, this is an observational study
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Risk Factors and Mechanisms for Diabetes in Pancreatitis.Gastroenterology clinics of North America · 2025
    Review
  6. The Role of Pancreatitis Risk Genes in Endocrine Insufficiency Development After Acute Pancreatitis in Children.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
    Observational
  7. Article
  8. Alterations in exocrine pancreatic function after acute pancreatitis.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Joseph BejjaniDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Georgios I PapachristouDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Kathleen DunganDivision of Endocrinology, Diabetes & Metabolism, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Anna Evans PhillipsDivision of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Vikesh SinghDivision of Gastroenterology and Hepatology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Frederico Gs ToledoDivision of Endocrinology and Metabolism, University of Pittsburgh, Pittsburgh, PA, USA.
Samuel HanDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Somashekar G KrishnaDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Ali LahootiWeill Cornell Medical College, New York, NY, USA.
Peter J LeeDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Jorge D MachicadoDivision of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA.
Melica NikahdDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Pedram ParagomiUPMC Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Mitch RamseyDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Dhiraj YadavDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Stacey CulpDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Phil A HartDivision of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address: philip.hart@osumc.edu.
The Ohio State University Wexner Medical Center · USThe Ohio State University · USUniversity of Pittsburgh · USCornell University · USJohns Hopkins University · USUniversity of Michigan · USUPMC Hillman Cancer Center · US

Funding

UPMC Clinical Center for the Study of Diabetes After Acute PancreatitisU01DK127377 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Frederico G. S. Toledo, Dhiraj Yadav · 2020 to 2026
$2.4M
Epidemiology and Pathophysiology of Acute Pancreatitis-related Diabetes MellitusU01DK127388 · NIDDK · OHIO STATE UNIVERSITY · PI Kathleen Marie Dungan, Philip A. Hart · 2020 to 2026
$2.4M
Clinical, Radiologic and Biochemical Factors Related to Diabetes Development after Acute PancreatitisU01DK127400 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI Rita R Kalyani, ZHAOLI SUN · 2020 to 2026
$2.3M
NIDDK NIH HHS U01 DK127377NIDDK NIH HHS U01 DK127388NIDDK NIH HHS U01 DK127400
6 · The paper itself

Abstract

Diabetes mellitus following an episode of acute pancreatitis (AP) is an increasingly discussed complication, but there are sparse prospective data on the incidence and risk factors. We evaluated data from a prospective, multicenter observational cohort study that enrolled adults hospitalized with AP between 2017 and 2021 and followed them for one year. Ninety-eight participants who completed 12-month follow-up were included in this analysis. Diabetes status was assessed using a combination of measured glycated hemoglobin (HbA1c) at predetermined time intervals or physician diagnosis. In 68 participants without diabetes at enrollment, the cumulative incidence of new-onset diabetes was 4.4 % (n = 3) at 3 months and 10.3 % (n = 7) at 12 months. No differences were observed in demographic or pancreatitis-related characteristics between those who did versus did not develop diabetes, in part due to small sample size. In summary, new-onset diabetes was identified in approximately 10 % within one year after an episode of AP. Larger prospective studies are needed to further define the incidence, risk factors, and mechanisms of diabetes and pre-diabetes following AP. NCT03063398.

Indexed as

Diabetes MellitusPancreatitisAcute DiseaseAdultHumansProspective StudiesRisk FactorsHyperglycemiaPre-diabetes

Identifiers

PMID37839923
PMCPMC10843459
OpenAlexW4387502079

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.