Evidence map›Paper›PMID 37839524›Full record

ArticleJournal of sport and health science2024

Association between baseline levels of muscular strength and risk of stroke in later life: The Cooper Center Longitudinal Study.

Stephen W Farrell, David Leonard, Qing Li, Carolyn E Barlow, Kerem Shuval, Jarett D Berry, Andjelka Pavlovic, Laura F DeFina

Open access · diamondAbstract read
In one paragraph

Article in Journal of sport and health science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Stephen W FarrellResearch Division, The Cooper Institute, Dallas, TX 75230, USA. Electronic address: steve.farrell57@outlook.com.
David LeonardResearch Division, The Cooper Institute, Dallas, TX 75230, USA.
Qing LiResearch Division, The Cooper Institute, Dallas, TX 75230, USA.
Carolyn E BarlowResearch Division, The Cooper Institute, Dallas, TX 75230, USA.
Kerem ShuvalResearch Division, The Cooper Institute, Dallas, TX 75230, USA.
Jarett D BerryDepartment of Internal Medicine, University of Texas at Tyler School of Medicine, Tyler, TX 75799, USA.
Andjelka PavlovicResearch Division, The Cooper Institute, Dallas, TX 75230, USA.
Laura F DeFinaResearch Division, The Cooper Institute, Dallas, TX 75230, USA.
Cooper Institute · USThe University of Texas at Tyler · US

Funding

UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI JAY D. HORTON · 2022 to 2026
$7.4M
NIDDK NIH HHS P30 DK127984
6 · The paper itself

Abstract

backgroundMuscular strength is an important component of physical fitness. We evaluated the relationship between baseline muscular strength and risk of stroke among adults who were aged ≥65 years during follow-up.

methodsWe included 7627 healthy adults (mean age = 43.9 years, 86.0% male) underwent a baseline physical examination between 1980 and 1989. Muscular strength was determined by 1-repetition maximum measures for bench press and leg press and categorized into age- and sex-specific tertiles for each measure. Cardiorespiratory fitness (CRF) was assessed via a maximal treadmill exercise test. Those enrolled in fee-for-service Medicare from 1999 to 2019 were included in the analyses. Associations between baseline strength and stroke outcomes were estimated using a modified Cox proportional hazards model. In a secondary analysis, we examined stroke risk by categories of CRF where Quintile 1 = low, Quintiles 2-3 = moderate, and Quintiles 4-5 = high CRF based on age and sex.

resultsAfter 70,072 person-years of Medicare follow-up, there were 1211 earliest indications of incident stroke. In multivariable analyses, the hazard ratio (95% confidence interval (95%CI)) for stroke across bench press categories were 1.0 (referent), 0.96 (0.83-1.11), and 0.89 (0.77-1.04), respectively (p trend = 0.14). The trend across categories of leg press was also non-significant (p trend = 0.79). Adjusted hazard ratio (95%CI) for stroke across ordered CRF categories were 1.0 (referent), 0.90 (0.71-1.13), and 0.72 (0.57-0.92) (p trend < 0.01).

conclusionWhile meeting public health guidelines for muscular strengthening activities is likely to improve muscular strength as well as many health outcomes in older adults, performing such activities may not be helpful in preventing stroke. Conversely, meeting guidelines for aerobic activity is likely to improve CRF and lower stroke risk.

Indexed as

Cardiorespiratory FitnessMuscle StrengthStrokeAdultAgedExercise TestFemaleHumansLongitudinal StudiesMaleMedicareMiddle AgedProportional Hazards ModelsRisk FactorsUnited StatesCardiorespiratory fitnessMedicareMuscular strengthStroke

Identifiers

PMID37839524
PMCPMC11282351
OpenAlexW4387611435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.