Evidence map›Paper›PMID 37839180›Full record

ArticleCell calcium2023

Structural insights into the TRPV4-RhoA complex offer clues to solve the puzzle of TRPV4 channelopathies.

Xueming Hu, Hongzhen Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell calcium, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. TRPV4 Channel Modulators as Potential Drug Candidates for Cystic Fibrosis.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xueming HuThe Kimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Mark Lebwohl Center for Neuroinflammation and Sensation, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hongzhen HuThe Kimberly and Eric J. Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Mark Lebwohl Center for Neuroinflammation and Sensation, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: hongzhen.hu@mssm.edu.

Funding

TARGETING THE TRANSIENT RECEPTOR POTENTIAL CHANNELS TO IMPROVE BOWEL DYSFUNCTIONR01DK103901 · NIDDK · WASHINGTON UNIVERSITY · PI HU, HONGZHEN · 2015 to 2023
$3.4M
Deciphering the Piezo2-Merkel cell signaling mechanisms in itchR01AR077183 · NIAMS · WASHINGTON UNIVERSITY · PI HU, HONGZHEN · 2020 to 2024
$2.6M
MECHANISMS OF TRPV4-MEDIATED NEUROPATHIC PAINR01AA027065 · NIAAA · WASHINGTON UNIVERSITY · PI HU, HONGZHEN · 2018 to 2022
$2.5M
NIAAA NIH HHS R01 AA027065NIAMS NIH HHS R01 AR077183NIDDK NIH HHS R01 DK103901
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChannelopathiesTRPV Cation ChannelsHumansMutationTRPV4 protein, humanTRPV Cation Channels

Identifiers

PMID37839180
PMCPMC11192545

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.