Evidence map›Paper›PMID 37839020›Full record

ArticleMycopathologia2023

Pulmonary Histoplasmosis in People Living with Human Immunodeficiency Virus in French Guiana: Clinical Epidemiology, Medical Imaging and Prognostic.

Morgane Bourne-Watrin, Antoine Adenis, Gary Doppelt, Magaly Zappa, Loïc Epelboin, Mathieu Nacher, Jeanne Bigot, Kinan Drak Alsibai, Romain Blaizot, Denis Blanchet and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Mycopathologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Predictors of mortality in hospitalized patients with disseminated histoplasmosis.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Morgane Bourne-WatrinService de Dermatologie-Vénérologie, Centre Hospitalier de Cayenne, Cayenne, France. mbournewatrin@yahoo.fr.ORCID http://orcid.org/0000-0003-2216-9715
Antoine AdenisCentre d'Investigation Clinique Antilles Guyane, Inserm CIC 1424, Centre Hospitalier de Cayenne, Cayenne, France.
Gary DoppeltService de Radiologie, Centre Hospitalier de Cayenne, Cayenne, France.
Magaly ZappaService de Radiologie, Centre Hospitalier de Cayenne, Cayenne, France.
Loïc EpelboinCentre d'Investigation Clinique Antilles Guyane, Inserm CIC 1424, Centre Hospitalier de Cayenne, Cayenne, France.
Mathieu NacherCentre d'Investigation Clinique Antilles Guyane, Inserm CIC 1424, Centre Hospitalier de Cayenne, Cayenne, France.
Jeanne BigotService de Parasitologie-Mycologie, Centre Hospitalier Saint Antoine APHP, Paris, France.
Kinan Drak AlsibaiLaboratoire d'Anatomie et Cytologie Pathologique, Centre Hospitalier de Cayenne, Cayenne, France.
Romain BlaizotService de Dermatologie-Vénérologie, Centre Hospitalier de Cayenne, Cayenne, France.
Denis BlanchetLaboratoire de Parasitologie-Mycologie, Centre Hospitalier de Cayenne, Cayenne, France.
Magalie DemarLaboratoire de Parasitologie-Mycologie, Centre Hospitalier de Cayenne, Cayenne, France.
Geneviève GuillotService de Médecine B, Centre Hospitalier de Cayenne, Cayenne, France.
Félix DjossouUnité des Maladies Infectieuses et Tropicales, Centre Hospitalier de Cayenne, Cayenne, France.
Pierre CouppiéService de Dermatologie-Vénérologie, Centre Hospitalier de Cayenne, Cayenne, France.
Inserm · FRCentre Hospitalier Andrée Rosemon · GFSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHistoplasmosis is mainly described as a disseminated disease in people living with HIV (PLHIV). Compared to historical descriptions in immunocompetent individuals, knowledge is lacking on the detailed clinical and radiological findings and outcomes of pulmonary histoplasmosis (PH). Overlooked or misdiagnosed with other AIDS-defining condition, prognostic of PLHIV may be at risk because of inappropriate care.

methodsA retrospective multicentric study was conducted in PLHIV from French Guiana between January 1988 and October 2019. Proven PH were documented through mycological direct examination, culture, or histology. Patients with concomitant respiratory infections were excluded.

resultsAmong 65 patients, sex ratio M:F was 2.4 with a median age of 39 years [IQR 25-75%: 34-44]. Median CD4 count was 24 cells/mm

conclusionWhen faced with an interstitial lung disease on X-rays or a miliary pattern on CT-scans in advanced PLHIV, physicians in endemic areas, apart from tuberculosis or pneumocystosis, should include histoplasmosis as part of their differential diagnoses.

Indexed as

Acquired Immunodeficiency SyndromeAIDS-Related Opportunistic InfectionsHistoplasmosisLung Diseases, FungalLung Diseases, InterstitialPneumonia, PneumocystisAdultFrench GuianaHIVHumansPrognosisRetrospective StudiesTomography, X-Ray ComputedFrench GuianaHIVMiliaryNodulesPulmonary histoplasmosis

Identifiers

PMID37839020
PMCPMC10687118
OpenAlexW4387654633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.