Evidence map›Paper›PMID 37838808›Full record

ArticleScientific reports2023

Rapid detection of vaccinia virus using biofunctionalized fiber-optic ball-tip biosensors.

Aida Rakhimbekova, Baizak Kudaibergenov, Kuanysh Seitkamal, Aurora Bellone, Ayazhan Dauletova, Marzhan Sypabekova, Massimo Olivero, Guido Perrone, Antonia Radaelli, Carlo Zanotto and 3 more

Abstract read
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In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Aida RakhimbekovaDepartment of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, 010000, Astana, Kazakhstan.
Baizak KudaibergenovDepartment of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, 010000, Astana, Kazakhstan.
Kuanysh SeitkamalDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, 010000, Astana, Kazakhstan.
Aurora BelloneDepartment of Electronics and Telecommunications, Politecnico Di Torino, Turin, Italy.
Ayazhan DauletovaDepartment of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, 010000, Astana, Kazakhstan.
Marzhan SypabekovaDepartment of Electrical & Computer Engineering, Baylor University, Waco, TX, USA.
Massimo OliveroDepartment of Electronics and Telecommunications, Politecnico Di Torino, Turin, Italy.
Guido PerroneDepartment of Electronics and Telecommunications, Politecnico Di Torino, Turin, Italy.
Antonia Radaelli *Department of Medical Biotechnologies and Translational Medicine, Laboratory of Molecular Virology and Recombinant Vaccine Development, University of Milan, Via Vanvitelli 32, Milan, Italy.
Carlo Zanotto *Department of Medical Biotechnologies and Translational Medicine, Laboratory of Molecular Virology and Recombinant Vaccine Development, University of Milan, Via Vanvitelli 32, Milan, Italy.
Carlo De Giuli Morghen *Catholic University "Our Lady of Good Counsel", Rr. Dritan Hoxha, Tirana, Albania.
Luca Vangelista *Department of Biomedical Sciences, School of Medicine, Nazarbayev University, 010000, Astana, Kazakhstan.
Daniele Tosi *Department of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, 010000, Astana, Kazakhstan. daniele.tosi@nu.edu.kz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we present the development and biofunctionalization of a fiber-optic ball-resonator biosensor for the real-time detection of vaccinia poxvirus. We fabricated several ball-tip resonators, functionalized through a silanization process to immobilize two bioreceptors: the monoclonal anti-L1R antibody targeting the L1R protein, and the polyclonal rabbit serum antibodies targeting the whole vaccinia virus (VV) pathogen. Experimental measurements were carried out to detect VV in concentrations from 10

Indexed as

Biosensing TechniquesPoxviridaeVacciniaAnimalsFiber Optic TechnologyHumansRabbitsVaccinia virus

Identifiers

PMID37838808
PMCPMC10576743

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.