Evidence map›Paper›PMID 37838806›Full record

ArticleEuropean journal of clinical nutrition2024

Adding salt to foods and hazards of microvascular, cerebrovascular and cardiovascular diseases.

Mengyi Liu, Ziliang Ye, Panpan He, Sisi Yang, Yanjun Zhang, Chun Zhou, Yuanyuan Zhang, Fan Fan Hou, Xianhui Qin

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Article in European journal of clinical nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mengyi Liu *Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Ziliang Ye *Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Panpan HeDivision of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Sisi YangDivision of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Yanjun ZhangDivision of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Chun ZhouDivision of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Yuanyuan ZhangDivision of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Fan Fan HouDivision of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. ffhouguangzhou@163.com.ORCID 0000-0003-3117-7418
Xianhui QinDivision of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. pharmaqin@126.com.ORCID 0000-0001-7812-7982

Funding

National Natural Science Foundation of China (National Science Foundation of China) 81973133, 81730019
6 · The paper itself

Abstract

backgroundWe aimed to examine the association of the frequency of adding salt to foods and the hazards of the incidence and mortality risks for a range of vascular outcomes, including microvascular, cerebrovascular, and cardiovascular diseases.

methods438,307 participants from the UK Biobank who completed the questionnaire on the frequency of adding salt to foods and were free of vascular disease at baseline were enrolled. Information on the frequency of adding salt to foods (do not include salt used in cooking) was collected at baseline through a touch-screen questionnaire. The primary outcomes included incident microvascular diseases, cerebrovascular diseases, and cardiovascular diseases, respectively. The secondary outcomes included: (1) each component of these vascular diseases (10 components in total), (2) first occurrence of fatal and non-fatal vascular diseases.

resultsDuring a median follow-up of 12.1 years, a total of 17,169 (3.9%), 10,437 (2.4%), and 48,203 (11.0%) participants developed microvascular, cerebrovascular and cardiovascular diseases, respectively. Overall, the hazards of incident microvascular, cerebrovascular and cardiovascular diseases increased with the increasing frequency of adding salt to foods (all P for trend <0.001). Similar trends were found for the secondary outcomes. Moreover, the positive association of always adding salt to foods with hazard of cardiovascular diseases was stronger among current-smokers (P-interaction = 0.010), younger participants (P-interaction <0.001), and those with lower body mass index levels (P-interaction = 0.003).

conclusionsHigher frequency of adding salt to foods was associated with higher hazards of non-fatal and fatal microvascular, cerebrovascular and cardiovascular diseases, and each component of these vascular diseases.

Indexed as

Cardiovascular DiseasesVascular DiseasesFoodHumansRisk FactorsSodium Chloride, DietarySodium Chloride, Dietary

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.