Evidence map›Paper›PMID 37837558›Full record

Observational studyEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2023

Impact of surgical treatment on lipid metabolism in patients with lumbar spinal disorders: Prospective observational study.

Yukio Nakajima, Kurenai Hachiya, Takehiro Michikawa, Sota Nagai, Hiroki Takeda, Soya Kawabata, Atsushi Yoshioka, Hirona Kimata, Daiki Ikeda, Shinjiro Kaneko and 3 more

Open access · hybridAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Yukio NakajimaDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan.
Kurenai HachiyaDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan.
Takehiro MichikawaDepartment of Environmental and Occupational Health, School of Medicine, Toho University, Tokyo, Japan.
Sota NagaiDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan.
Hiroki TakedaDepartment of Spine and Spinal Cord Surgery, Fujita Health University, Toyoake, Japan.
Soya KawabataDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan.
Atsushi YoshiokaDepartment of Orthopaedic Surgery, Hachiya Orthopaedic Hospital, 2-4, Nagoya, Japan.
Hirona KimataCanon Medical Systems Corporation, Tokyo, Japan.
Daiki IkedaDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan.
Shinjiro KanekoDepartment of Spine and Spinal Cord Surgery, Fujita Health University, Toyoake, Japan.
Yoshiharu OhnoDepartment of Radiology, School of Medicine, Fujita Health University, Toyoake, Japan.
Yudo HachiyaDepartment of Orthopaedic Surgery, Hachiya Orthopaedic Hospital, 2-4, Nagoya, Japan.
Nobuyuki FujitaDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-Cho, Toyoake, Aichi, 470-1192, Japan. nfujita2007@gmail.com.
Fujita Health University Hospital · JPFujita Health University · JPCanon Medical Systems Corporation (Japan)Toho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIt is still unclear how lumbar spinal surgery affects the lipid metabolism of patients with lumbar spinal disorders (LSDs) such as lumbar spinal canal stenosis and lumbar disk herniation. The present study aimed to assess the impact of lumbar spinal surgery on lipid metabolism in patients with LSDs and clarify the factors associated with changes in visceral fat (VF) accumulation before and after lumbar spinal surgery.

methodsConsecutive patients with lumbar spinal surgery for LSDs were prospectively included. Abdominal computed tomography images and blood examination of the participants were evaluated before surgery and at 6 months and 1 year after surgery. The cross-sectional VF area (VFA) was measured at the level of the navel using computed tomography images. Blood examination items included triglycerides and high-density lipoprotein (HDL).

resultsThe study enrolled a total of 138 patients. Female patients with LSDs had significantly increased VFA and serum triglyceride levels after lumbar spinal surgery. On multivariable analysis, the group with > 100 cm

conclusionsThe present study demonstrated that patients with LSDs did not necessarily improve their lipid metabolism after lumbar spinal surgery. Instead, female patients with LSDs had significantly deteriorated lipid metabolism after lumbar spinal surgery. Finally, a worse preoperative walking ability was associated with the improvement in excess VF accumulation after lumbar spinal surgery.

Indexed as

Decompression, SurgicalSpinal StenosisCross-Sectional StudiesFemaleHumansLipid MetabolismLumbar VertebraeProspective StudiesTreatment OutcomeHigh-density lipoproteinJapanese Orthopaedic Association Back Pain Evaluation QuestionnaireLumbar disk herniationLumbar spinal canal stenosisLumbar spinal disordersLumbar spinal surgeryMetabolic syndromeTriglyceridesVisceral fatWalking ability

Identifiers

PMID37837558
OpenAlexW4387639676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.