Evidence map›Paper›PMID 37837184›Full record

ArticlePharmacology research & perspectives2023

Effects of (-)-MBP, a novel 5-HT

Preeti K Sathe, Gargi R Ramdasi, Kaylie Giammatteo, Harvens Beauzile, Shuyue Wang, Heng Zhang, Praveen Kulkarni, Raymond G Booth, Craig F Ferris

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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  7. Effects of (-)-MBP, a novel 5-HTPharmacology research & perspectives · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Preeti K SatheDepartment Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.
Gargi R RamdasiDepartment Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.
Kaylie GiammatteoDepartment Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.
Harvens BeauzileDepartment Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.
Shuyue WangDepartment Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.
Heng ZhangDepartment Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.
Praveen KulkarniCenter for Translational Neuroscience, Northeastern University, Boston, Massachusetts, USA.
Raymond G BoothDepartment Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.
Craig F FerrisDepartment Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA.ORCID 0000-0001-9744-5214
Northeastern University · US

Funding

Delineating the role of serotonin 5-HT2 receptors in opioid use disorders:Development of novel 5-HT2 modulators with translational studies in rodents andprimatesR01DA047130 · NIDA · NORTHEASTERN UNIVERSITY · PI BOOTH, RAYMOND G., KOHUT, STEPHEN JOHN · 2018 to 2022
$3.2M
Novel 5HT2C Agonist Drugs with 5HT2A Antagonist Activity for Cocaine AddictionR01DA023928 · NIDA · UNIVERSITY OF FLORIDA · PI BOOTH, RAYMOND G. · 2007 to 2010
$1.5M
Training Program on Development of Medications for Substance Use DisorderT32DA055553 · NIDA · NORTHEASTERN UNIVERSITY · PI Raymond G. Booth, Alexandros Makriyannis · 2022 to 2026
$1.3M
NIDA NIH HHS R01 DA023928NIDA NIH HHS R01 DA047130NIDA NIH HHS T32 DA055553NIH HHS R01-047130
6 · The paper itself

Abstract

A novel serotonin ligand (-)-MBP was developed for the treatment of schizophrenia that has 5-HT

Indexed as

Drug Inverse AgonismSerotoninAnimalsBrainLigandsMaleMiceWakefulnessLigandsSerotoninBOLD imagingPapez circuitschizophreniaserotoninthalamus

Identifiers

PMID37837184
PMCPMC10576165
OpenAlexW4387637150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.