Evidence map›Paper›PMID 37836706›Full record

ArticleMolecules (Basel, Switzerland)2023

Measurement of Urinary Gc-Globulin by a Fluorescence ELISA Technique: Method Validation and Clinical Evaluation in Septic Patients-A Pilot Study.

Tamás Kőszegi, Zoltán Horváth-Szalai, Dániel Ragán, Brigitta Kósa, Balázs Szirmay, Csilla Kurdi, Gábor L Kovács, Diána Mühl

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tamás KőszegiDepartment of Laboratory Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0002-3910-5745
Zoltán Horváth-SzalaiDepartment of Laboratory Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.ORCID 0009-0008-4568-6858
Dániel RagánDepartment of Laboratory Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0002-5429-0168
Brigitta KósaDepartment of Laboratory Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Balázs SzirmayDepartment of Laboratory Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Csilla KurdiJános Szentágothai Research Center, University of Pécs, 7624 Pécs, Hungary.
Gábor L KovácsDepartment of Laboratory Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0001-5298-5401
Diána MühlDepartment of Anesthesiology and Intensive Therapy, Medical School, University of Pécs, 7624 Pécs, Hungary.
University of Pecs · HU

Funding

National Laboratory on Human Reproduction RRF-2.3.1-21-2022-00012University of Pécs, Hungary EFOP 3.6.1-16-2016-00004University of Pécs Medical School, Hungary PTE ÁOK-KA No: 2019/300825
6 · The paper itself

Abstract

A major complication of sepsis is the development of acute kidney injury (AKI). In case of acute tubular damage, Gc-globulin, a known serum sepsis marker is increasingly filtrated into the urine therefore, urinary Gc-globulin (u-Gc) levels may predict septic AKI. We developed and validated a competitive fluorescence ELISA method for u-Gc measurement. Serum and urine samples from septic patients were collected in three consecutive days (T1, T2, T3) and data were compared to controls. Intra- and interassay imprecisions were CV < 14% and CV < 20%, respectively, with a recovery close to 100%. Controls and septic patients differed (

Indexed as

Acute Kidney InjuryGlobulinsSepsisBiomarkersCreatinineEnzyme-Linked Immunosorbent AssayHumansPilot ProjectsBiomarkersCreatinineGlobulinsacute kidney injuryfluorescence ELISApredictive valuesepsisurinary Gc-globulin

Identifiers

PMID37836706
PMCPMC10574505
OpenAlexW4387169811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.